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Metabolomics integrated elementary flux mode analysis in large metabolic networks
Elementary flux modes (EFMs) are non-decomposable steady-state pathways in metabolic networks. They characterize phenotypes, quantify robustness or identify engineering targets. An EFM analysis (EFMA) is currently restricted to medium-scale models, as the number of EFMs explodes with the network...
Autores principales: | Gerstl, Matthias P., Ruckerbauer, David E., Mattanovich, Diethard, Jungreuthmayer, Christian, Zanghellini, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354105/ https://www.ncbi.nlm.nih.gov/pubmed/25754258 http://dx.doi.org/10.1038/srep08930 |
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