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Morphology cluster and prediction of growth of human brain pyramidal neurons★

Predicting neuron growth is valuable to understand the morphology of neurons, thus it is helpful in the research of neuron classification. This study sought to propose a new method of predicting the growth of human neurons using 1 907 sets of data in human brain pyramidal neurons obtained from the w...

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Detalles Bibliográficos
Autores principales: Yu, Chao, Han, Zengxin, Zeng, Wencong, Liu, Shenquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354113/
https://www.ncbi.nlm.nih.gov/pubmed/25806056
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.01.006
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author Yu, Chao
Han, Zengxin
Zeng, Wencong
Liu, Shenquan
author_facet Yu, Chao
Han, Zengxin
Zeng, Wencong
Liu, Shenquan
author_sort Yu, Chao
collection PubMed
description Predicting neuron growth is valuable to understand the morphology of neurons, thus it is helpful in the research of neuron classification. This study sought to propose a new method of predicting the growth of human neurons using 1 907 sets of data in human brain pyramidal neurons obtained from the website of NeuroMorpho.Org. First, we analyzed neurons in a morphology field and used an expectation-maximization algorithm to specify the neurons into six clusters. Second, naive Bayes classifier was used to verify the accuracy of the expectation-maximization algorithm. Experiment results proved that the cluster groups here were efficient and feasible. Finally, a new method to rank the six expectation-maximization algorithm clustered classes was used in predicting the growth of human pyramidal neurons.
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spelling pubmed-43541132015-03-24 Morphology cluster and prediction of growth of human brain pyramidal neurons★ Yu, Chao Han, Zengxin Zeng, Wencong Liu, Shenquan Neural Regen Res Research and Report: Neurogensis and Neural Plasticicty Predicting neuron growth is valuable to understand the morphology of neurons, thus it is helpful in the research of neuron classification. This study sought to propose a new method of predicting the growth of human neurons using 1 907 sets of data in human brain pyramidal neurons obtained from the website of NeuroMorpho.Org. First, we analyzed neurons in a morphology field and used an expectation-maximization algorithm to specify the neurons into six clusters. Second, naive Bayes classifier was used to verify the accuracy of the expectation-maximization algorithm. Experiment results proved that the cluster groups here were efficient and feasible. Finally, a new method to rank the six expectation-maximization algorithm clustered classes was used in predicting the growth of human pyramidal neurons. Medknow Publications & Media Pvt Ltd 2012-01-05 /pmc/articles/PMC4354113/ /pubmed/25806056 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.01.006 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research and Report: Neurogensis and Neural Plasticicty
Yu, Chao
Han, Zengxin
Zeng, Wencong
Liu, Shenquan
Morphology cluster and prediction of growth of human brain pyramidal neurons★
title Morphology cluster and prediction of growth of human brain pyramidal neurons★
title_full Morphology cluster and prediction of growth of human brain pyramidal neurons★
title_fullStr Morphology cluster and prediction of growth of human brain pyramidal neurons★
title_full_unstemmed Morphology cluster and prediction of growth of human brain pyramidal neurons★
title_short Morphology cluster and prediction of growth of human brain pyramidal neurons★
title_sort morphology cluster and prediction of growth of human brain pyramidal neurons★
topic Research and Report: Neurogensis and Neural Plasticicty
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354113/
https://www.ncbi.nlm.nih.gov/pubmed/25806056
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.01.006
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