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Morphology cluster and prediction of growth of human brain pyramidal neurons★
Predicting neuron growth is valuable to understand the morphology of neurons, thus it is helpful in the research of neuron classification. This study sought to propose a new method of predicting the growth of human neurons using 1 907 sets of data in human brain pyramidal neurons obtained from the w...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354113/ https://www.ncbi.nlm.nih.gov/pubmed/25806056 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.01.006 |
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author | Yu, Chao Han, Zengxin Zeng, Wencong Liu, Shenquan |
author_facet | Yu, Chao Han, Zengxin Zeng, Wencong Liu, Shenquan |
author_sort | Yu, Chao |
collection | PubMed |
description | Predicting neuron growth is valuable to understand the morphology of neurons, thus it is helpful in the research of neuron classification. This study sought to propose a new method of predicting the growth of human neurons using 1 907 sets of data in human brain pyramidal neurons obtained from the website of NeuroMorpho.Org. First, we analyzed neurons in a morphology field and used an expectation-maximization algorithm to specify the neurons into six clusters. Second, naive Bayes classifier was used to verify the accuracy of the expectation-maximization algorithm. Experiment results proved that the cluster groups here were efficient and feasible. Finally, a new method to rank the six expectation-maximization algorithm clustered classes was used in predicting the growth of human pyramidal neurons. |
format | Online Article Text |
id | pubmed-4354113 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-43541132015-03-24 Morphology cluster and prediction of growth of human brain pyramidal neurons★ Yu, Chao Han, Zengxin Zeng, Wencong Liu, Shenquan Neural Regen Res Research and Report: Neurogensis and Neural Plasticicty Predicting neuron growth is valuable to understand the morphology of neurons, thus it is helpful in the research of neuron classification. This study sought to propose a new method of predicting the growth of human neurons using 1 907 sets of data in human brain pyramidal neurons obtained from the website of NeuroMorpho.Org. First, we analyzed neurons in a morphology field and used an expectation-maximization algorithm to specify the neurons into six clusters. Second, naive Bayes classifier was used to verify the accuracy of the expectation-maximization algorithm. Experiment results proved that the cluster groups here were efficient and feasible. Finally, a new method to rank the six expectation-maximization algorithm clustered classes was used in predicting the growth of human pyramidal neurons. Medknow Publications & Media Pvt Ltd 2012-01-05 /pmc/articles/PMC4354113/ /pubmed/25806056 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.01.006 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research and Report: Neurogensis and Neural Plasticicty Yu, Chao Han, Zengxin Zeng, Wencong Liu, Shenquan Morphology cluster and prediction of growth of human brain pyramidal neurons★ |
title | Morphology cluster and prediction of growth of human brain pyramidal neurons★ |
title_full | Morphology cluster and prediction of growth of human brain pyramidal neurons★ |
title_fullStr | Morphology cluster and prediction of growth of human brain pyramidal neurons★ |
title_full_unstemmed | Morphology cluster and prediction of growth of human brain pyramidal neurons★ |
title_short | Morphology cluster and prediction of growth of human brain pyramidal neurons★ |
title_sort | morphology cluster and prediction of growth of human brain pyramidal neurons★ |
topic | Research and Report: Neurogensis and Neural Plasticicty |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354113/ https://www.ncbi.nlm.nih.gov/pubmed/25806056 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.01.006 |
work_keys_str_mv | AT yuchao morphologyclusterandpredictionofgrowthofhumanbrainpyramidalneurons AT hanzengxin morphologyclusterandpredictionofgrowthofhumanbrainpyramidalneurons AT zengwencong morphologyclusterandpredictionofgrowthofhumanbrainpyramidalneurons AT liushenquan morphologyclusterandpredictionofgrowthofhumanbrainpyramidalneurons |