p53 Suppresses Tetraploid Development in Mice

Mammalian tetraploid embryos die in early development because of defects in the epiblast. Experiments with diploid/tetraploid chimeric mice, obtained via the aggregation of embryonic stem cells, clarified that while tetraploid cells are excluded from epiblast derivatives, diploid embryos with tetrap...

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Detalles Bibliográficos
Autores principales: Horii, Takuro, Yamamoto, Masamichi, Morita, Sumiyo, Kimura, Mika, Nagao, Yasumitsu, Hatada, Izuho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354145/
https://www.ncbi.nlm.nih.gov/pubmed/25752699
http://dx.doi.org/10.1038/srep08907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354145/
https://www.ncbi.nlm.nih.gov/pubmed/25752699
http://dx.doi.org/10.1038/srep08907

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