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Changes in Serum Biochemical Factors Associated with Opium Addiction after Addiction Desertion
BACKGROUND: The long time use of opium has some effects on serums biochemical factors, the determination of this variation is a new approach in understanding off addiction and relive of drug abuser health. Hence in this study, these indicators in person who were withdrawing of opium have been studie...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kerman University of Medical Sciences
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354219/ https://www.ncbi.nlm.nih.gov/pubmed/25984281 |
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author | Afarinesh, Mohammad Reza Haghpanah, Tahereh Divsalar, Kouros Dehyadegary, Elham Shaikh-Aleslami, Azar Mahmoodi, Majid |
author_facet | Afarinesh, Mohammad Reza Haghpanah, Tahereh Divsalar, Kouros Dehyadegary, Elham Shaikh-Aleslami, Azar Mahmoodi, Majid |
author_sort | Afarinesh, Mohammad Reza |
collection | PubMed |
description | BACKGROUND: The long time use of opium has some effects on serums biochemical factors, the determination of this variation is a new approach in understanding off addiction and relive of drug abuser health. Hence in this study, these indicators in person who were withdrawing of opium have been studied. METHODS: In this cross-sectional study bloods biochemical factors such as fasting blood sugar (FBS), sodium (Na), calcium (Ca), uric acid (UA), blood urea nitrogen (BUN), creatinine, cholesterol, total protein, and fibrinogen in three groups serum were studied: (1) Who had been permanent opium users more than 2 years (case). (2) Dependent person who has taken one month addiction withdrawal course (control). (3) A healthy group that had been demographically similar to the other groups. FINDINGS: According to these study findings, FBS serum level in the case group is lower than control group. Serum level of Na, creatinine, and blood triglyceride (TG) in case study are higher than group control. Concentration of potassium, Ca, UA, BUN, cholesterol, total serum protein, fibrinogen, and thrombin time in case study and group control showed no significant difference. Also, in withdrawing case serum level of Na, Ca, UA, BUN, creatinine, and TG significantly increase and thrombin time decrease. CONCLUSION: According to this study not only the longtime use of opium but also opium with drawerin opium dependent people can change their serum biochemical factors. So recognition, treatment, and prevention of this change could be a new step in improving of health and condition of patients. |
format | Online Article Text |
id | pubmed-4354219 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Kerman University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-43542192015-05-15 Changes in Serum Biochemical Factors Associated with Opium Addiction after Addiction Desertion Afarinesh, Mohammad Reza Haghpanah, Tahereh Divsalar, Kouros Dehyadegary, Elham Shaikh-Aleslami, Azar Mahmoodi, Majid Addict Health Original Article BACKGROUND: The long time use of opium has some effects on serums biochemical factors, the determination of this variation is a new approach in understanding off addiction and relive of drug abuser health. Hence in this study, these indicators in person who were withdrawing of opium have been studied. METHODS: In this cross-sectional study bloods biochemical factors such as fasting blood sugar (FBS), sodium (Na), calcium (Ca), uric acid (UA), blood urea nitrogen (BUN), creatinine, cholesterol, total protein, and fibrinogen in three groups serum were studied: (1) Who had been permanent opium users more than 2 years (case). (2) Dependent person who has taken one month addiction withdrawal course (control). (3) A healthy group that had been demographically similar to the other groups. FINDINGS: According to these study findings, FBS serum level in the case group is lower than control group. Serum level of Na, creatinine, and blood triglyceride (TG) in case study are higher than group control. Concentration of potassium, Ca, UA, BUN, cholesterol, total serum protein, fibrinogen, and thrombin time in case study and group control showed no significant difference. Also, in withdrawing case serum level of Na, Ca, UA, BUN, creatinine, and TG significantly increase and thrombin time decrease. CONCLUSION: According to this study not only the longtime use of opium but also opium with drawerin opium dependent people can change their serum biochemical factors. So recognition, treatment, and prevention of this change could be a new step in improving of health and condition of patients. Kerman University of Medical Sciences 2014 /pmc/articles/PMC4354219/ /pubmed/25984281 Text en © 2014 Kerman University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly. |
spellingShingle | Original Article Afarinesh, Mohammad Reza Haghpanah, Tahereh Divsalar, Kouros Dehyadegary, Elham Shaikh-Aleslami, Azar Mahmoodi, Majid Changes in Serum Biochemical Factors Associated with Opium Addiction after Addiction Desertion |
title | Changes in Serum Biochemical Factors Associated with Opium Addiction after Addiction Desertion |
title_full | Changes in Serum Biochemical Factors Associated with Opium Addiction after Addiction Desertion |
title_fullStr | Changes in Serum Biochemical Factors Associated with Opium Addiction after Addiction Desertion |
title_full_unstemmed | Changes in Serum Biochemical Factors Associated with Opium Addiction after Addiction Desertion |
title_short | Changes in Serum Biochemical Factors Associated with Opium Addiction after Addiction Desertion |
title_sort | changes in serum biochemical factors associated with opium addiction after addiction desertion |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354219/ https://www.ncbi.nlm.nih.gov/pubmed/25984281 |
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