The Functional Anatomy of Psychomotor Disturbances in Major Depressive Disorder

Psychomotor disturbances (PMD) are a classic feature of depressive disorder that provides rich clinical information. The aim our narrative review was to characterize the functional anatomy of PMD by summarizing findings from neuroimaging studies. We found evidence across several neuroimaging modalit...

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Detalles Bibliográficos
Autores principales: Liberg, Benny, Rahm, Christoffer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354237/
https://www.ncbi.nlm.nih.gov/pubmed/25806006
http://dx.doi.org/10.3389/fpsyt.2015.00034
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author Liberg, Benny
Rahm, Christoffer
author_facet Liberg, Benny
Rahm, Christoffer
author_sort Liberg, Benny
collection PubMed
description Psychomotor disturbances (PMD) are a classic feature of depressive disorder that provides rich clinical information. The aim our narrative review was to characterize the functional anatomy of PMD by summarizing findings from neuroimaging studies. We found evidence across several neuroimaging modalities that suggest involvement of fronto-striatal neurocircuitry, and monoaminergic pathways and metabolism. We suggest that PMD in major depressive disorder emerge from an alteration of limbic signals, which influence emotion, volition, higher-order cognitive functions, and movement.
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spelling pubmed-43542372015-03-24 The Functional Anatomy of Psychomotor Disturbances in Major Depressive Disorder Liberg, Benny Rahm, Christoffer Front Psychiatry Psychiatry Psychomotor disturbances (PMD) are a classic feature of depressive disorder that provides rich clinical information. The aim our narrative review was to characterize the functional anatomy of PMD by summarizing findings from neuroimaging studies. We found evidence across several neuroimaging modalities that suggest involvement of fronto-striatal neurocircuitry, and monoaminergic pathways and metabolism. We suggest that PMD in major depressive disorder emerge from an alteration of limbic signals, which influence emotion, volition, higher-order cognitive functions, and movement. Frontiers Media S.A. 2015-03-10 /pmc/articles/PMC4354237/ /pubmed/25806006 http://dx.doi.org/10.3389/fpsyt.2015.00034 Text en Copyright © 2015 Liberg and Rahm. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychiatry
Liberg, Benny
Rahm, Christoffer
The Functional Anatomy of Psychomotor Disturbances in Major Depressive Disorder
title The Functional Anatomy of Psychomotor Disturbances in Major Depressive Disorder
title_full The Functional Anatomy of Psychomotor Disturbances in Major Depressive Disorder
title_fullStr The Functional Anatomy of Psychomotor Disturbances in Major Depressive Disorder
title_full_unstemmed The Functional Anatomy of Psychomotor Disturbances in Major Depressive Disorder
title_short The Functional Anatomy of Psychomotor Disturbances in Major Depressive Disorder
title_sort functional anatomy of psychomotor disturbances in major depressive disorder
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354237/
https://www.ncbi.nlm.nih.gov/pubmed/25806006
http://dx.doi.org/10.3389/fpsyt.2015.00034
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