Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice

Fsp27 is a lipid droplet-associated protein almost exclusively expressed in adipocytes where it facilitates unilocular lipid droplet formation. In mice, Fsp27 deficiency is associated with increased basal lipolysis, ‘browning’ of white fat and a healthy metabolic profile, whereas a patient with cong...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Linkang, Park, Shi-Young, Xu, Li, Xia, Xiayu, Ye, Jing, Su, Lu, Jeong, Kyeong-Hoon, Hur, Jang Ho, Oh, Hyunhee, Tamori, Yoshikazu, Zingaretti, Cristina M., Cinti, Saverio, Argente, Jesús, Yu, Miao, Wu, Lizhen, Ju, Shenghong, Guan, Feifei, Yang, Hongyuan, Choi, Cheol Soo, Savage, David B., Li, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354252/
https://www.ncbi.nlm.nih.gov/pubmed/25565658
http://dx.doi.org/10.1038/ncomms6949

Ejemplares similares

Ejemplares similares