Inhibitory Effect of 3-(4-Hydroxyphenyl)-1-(thiophen-2-yl) prop-2-en-1-one, a Chalcone Derivative on MCP-1 Expression in Macrophages via Inhibition of ROS and Akt Signaling

Chalcones (1,3-diaryl-2-propen-1-ones), a subfamily of flavonoid, are widely known to possess potent anti-inflammatory and anti-oxidant properties. In this study, we investigated the effect of 3-(4-Hydroxyphenyl)-1-(thio3-(4-Hydroxyphenyl phen-2-yl)prop-2-en-1-one (TI-I-175), a synthetic chalcone de...

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Detalles Bibliográficos
Autores principales: Kim, Mi Jin, Kadayat, Taraman, Um, Yeon Ji, Jeong, Tae Cheon, Lee, Eung-Seok, Park, Pil-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354312/
https://www.ncbi.nlm.nih.gov/pubmed/25767679
http://dx.doi.org/10.4062/biomolther.2014.127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354312/
https://www.ncbi.nlm.nih.gov/pubmed/25767679
http://dx.doi.org/10.4062/biomolther.2014.127

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