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Identifying Driver Genes in Cancer by Triangulating Gene Expression, Gene Location, and Survival Data
Driver genes are directly responsible for oncogenesis and identifying them is essential in order to fully understand the mechanisms of cancer. However, it is difficult to delineate them from the larger pool of genes that are deregulated in cancer (ie, passenger genes). In order to address this probl...
Autores principales: | Rouam, Sigrid, Miller, Lance D, Karuturi, R Krishna Murthy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354331/ https://www.ncbi.nlm.nih.gov/pubmed/25949096 http://dx.doi.org/10.4137/CIN.S18302 |
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