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FASTAptamer: A Bioinformatic Toolkit for High-throughput Sequence Analysis of Combinatorial Selections

High-throughput sequence (HTS) analysis of combinatorial selection populations accelerates lead discovery and optimization and offers dynamic insight into selection processes. An underlying principle is that selection enriches high-fitness sequences as a fraction of the population, whereas low-fitne...

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Detalles Bibliográficos
Autores principales:	Alam, Khalid K, Chang, Jonathan L, Burke, Donald H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354339/ https://www.ncbi.nlm.nih.gov/pubmed/25734917 http://dx.doi.org/10.1038/mtna.2015.4

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