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CD160 is essential for NK-mediated IFN-γ production
NK-derived cytokines play important roles for natural killer (NK) function, but how the cytokines are regulated is poorly understood. CD160 is expressed on activated NK or T cells in humans but its function is unknown. We generated CD160-deficient mice to probe its function. Although CD160(−/−) mice...
Autores principales: | Tu, Tony C., Brown, Nicholas K., Kim, Tae-Jin, Wroblewska, Joanna, Yang, Xuanming, Guo, Xiaohuan, Lee, Seoyun Hyunji, Kumar, Vinay, Lee, Kyung-Mi, Fu, Yang-Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354368/ https://www.ncbi.nlm.nih.gov/pubmed/25711213 http://dx.doi.org/10.1084/jem.20131601 |
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