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Transcriptional Response of Polycomb Group Genes to Status Epilepticus in Mice is Modified by Prior Exposure to Epileptic Preconditioning
Exposure of the brain to brief, non-harmful seizures can activate protective mechanisms that temporarily generate a damage-refractory state. This process, termed epileptic tolerance, is associated with large-scale down-regulation of gene expression. Polycomb group (PcG) proteins are master controlle...
Autores principales: | Reynolds, James P., Miller-Delaney, Suzanne F. C., Jimenez-Mateos, Eva M., Sano, Takanori, McKiernan, Ross C., Simon, Roger P., Henshall, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354380/ https://www.ncbi.nlm.nih.gov/pubmed/25806020 http://dx.doi.org/10.3389/fneur.2015.00046 |
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