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Effect of a single nucleotide polymorphism in miR-146a on COX-2 protein expression and lung function in smokers with chronic obstructive pulmonary disease

OBJECTIVE: To evaluate the effect of a single nucleotide polymorphism (rs2910164) in the miR-146a precursor on the expression level of miR-146a, cyclooxygenase-2 (COX2), and production of prostaglandin E2 (PGE2) in lung tissue harvested from smokers with chronic obstructive pulmonary disease, as wel...

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Detalles Bibliográficos
Autores principales:	Wang, Ran, Li, Min, Zhou, Sijing, Zeng, Daxiong, Xu, Xuan, Xu, Rui, Sun, Gengyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354402/ https://www.ncbi.nlm.nih.gov/pubmed/25767384 http://dx.doi.org/10.2147/COPD.S74345

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