Cargando…

Nuclear-encoded factors involved in post-transcriptional processing and modification of mitochondrial tRNAs in human disease

The human mitochondrial genome (mtDNA) encodes 22 tRNAs (mt-tRNAs) that are necessary for the intraorganellar translation of the 13 mtDNA-encoded subunits of the mitochondrial respiratory chain complexes. Maturation of mt-tRNAs involves 5′ and 3′ nucleolytic excision from precursor RNAs, as well as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Powell, Christopher A., Nicholls, Thomas J., Minczuk, Michal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354410/ https://www.ncbi.nlm.nih.gov/pubmed/25806043 http://dx.doi.org/10.3389/fgene.2015.00079

Ejemplares similares

tRNAs as regulators of biological processes
por: Raina, Medha, et al.
Publicado: (2014)

A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs
por: Suzuki, Takeo, et al.
Publicado: (2014)

Maturation of selected human mitochondrial tRNAs requires deadenylation
por: Pearce, Sarah F, et al.
Publicado: (2017)

Human mitochondrial ribosomes can switch structural tRNAs – but when and why?
por: Chrzanowska-Lightowlers, Zofia, et al.
Publicado: (2017)

m(1)A Post-Transcriptional Modification in tRNAs
por: Oerum, Stephanie, et al.
Publicado: (2017)

NSUN2 introduces 5-methylcytosines in mammalian mitochondrial tRNAs
por: Van Haute, Lindsey, et al.
Publicado: (2019)

An extended dsRBD is required for post-transcriptional modification in human tRNAs
por: Bou-Nader, Charles, et al.
Publicado: (2015)

Novel Genomic and Evolutionary Perspective of Cyanobacterial tRNAs
por: Mohanta, Tapan K., et al.
Publicado: (2017)

Losing the stem-loop structure from metazoan mitochondrial tRNAs and co-evolution of interacting factors
por: Watanabe, Yoh-ichi, et al.
Publicado: (2014)

Corrigendum: Novel Genomic and Evolutionary Perspective of Cyanobacterial tRNAs
por: Mohanta, Tapan K., et al.
Publicado: (2020)

tRNA Fragments Populations Analysis in Mutants Affecting tRNAs Processing and tRNA Methylation
por: Molla-Herman, Anahi, et al.
Publicado: (2020)

Biosynthesis and Degradation of Sulfur Modifications in tRNAs
por: Shigi, Naoki
Publicado: (2021)

Analyses of Genomic tRNA Reveal Presence of Novel tRNAs in Oryza sativa
por: Mohanta, Tapan K., et al.
Publicado: (2017)

Methyltransferase METTL8 is required for 3-methylcytosine modification in human mitochondrial tRNAs
por: Lentini, Jenna M., et al.
Publicado: (2022)

Undetected antisense tRNAs in mitochondrial genomes?
por: Seligmann, Hervé
Publicado: (2010)

Armless mitochondrial tRNAs in Enoplea (Nematoda)
por: Jühling, Frank, et al.
Publicado: (2012)

tRNAs Promote Nuclear Import of HIV-1 Intracellular Reverse Transcription Complexes
por: Zaitseva, Lyubov, et al.
Publicado: (2006)

Mechanism of expanding the decoding capacity of tRNAs by modification of uridines
por: Weixlbaumer, Albert, et al.
Publicado: (2007)

To be or not to be modified: Miscellaneous aspects influencing nucleotide modifications in tRNAs
por: Barraud, Pierre, et al.
Publicado: (2019)

Complete chemical structures of human mitochondrial tRNAs
por: Suzuki, Takeo, et al.
Publicado: (2020)

Mitochondrial transcript maturation and its disorders
por: Van Haute, Lindsey, et al.
Publicado: (2015)

Retrograde tRNAs
por: Tuma, Rabiya S.
Publicado: (2005)

Transcriptional Analysis of Nuclear-Encoded Mitochondrial Genes in Eight Neurodegenerative Disorders: The Analysis of Seven Diseases in Reference to Friedreich’s Ataxia
por: Elsadany, Muhammad, et al.
Publicado: (2021)

DALRD3 encodes a protein mutated in epileptic encephalopathy that targets arginine tRNAs for 3-methylcytosine modification
por: Lentini, Jenna M., et al.
Publicado: (2020)

Systemic Bioinformatic Analyses of Nuclear-Encoded Mitochondrial Genes in Hypertrophic Cardiomyopathy
por: Tan, Zhaochong, et al.
Publicado: (2021)

Modification of orthogonal tRNAs: unexpected consequences for sense codon reassignment
por: Biddle, Wil, et al.
Publicado: (2016)

Queuosine modification protects cognate tRNAs against ribonuclease cleavage
por: Wang, Xiaoyun, et al.
Publicado: (2018)

Recent Advances in Our Understanding of the Biosynthesis of Sulfur Modifications in tRNAs
por: Shigi, Naoki
Publicado: (2018)

Tissue-specific expression atlas of murine mitochondrial tRNAs
por: He, Qiufen, et al.
Publicado: (2021)

Systematic Analysis of the Binding Surfaces between tRNAs and Their Respective Aminoacyl tRNA Synthetase Based on Structural and Evolutionary Data
por: Tamaki, Satoshi, et al.
Publicado: (2018)

Bioinformatics analysis suggests base modifications of tRNAs and miRNAs in Arabidopsis thaliana
por: Iida, Kei, et al.
Publicado: (2009)

tRNAs as Antibiotic Targets
por: Chopra, Shaileja, et al.
Publicado: (2014)

tRNAs taking charge
por: Cruz, Jonathan W., et al.
Publicado: (2015)

Processing of the seven valine tRNAs in Escherichia coli involves novel features of RNase P
por: Agrawal, Ankit, et al.
Publicado: (2014)

Hijacking tRNAs From Translation: Regulatory Functions of tRNAs in Mammalian Cell Physiology
por: Avcilar-Kucukgoze, Irem, et al.
Publicado: (2020)

Inosine modifications in human tRNAs are incorporated at the precursor tRNA level
por: Torres, Adrian Gabriel, et al.
Publicado: (2015)

Polyadenylation and degradation of structurally abnormal mitochondrial tRNAs in human cells
por: Toompuu, Marina, et al.
Publicado: (2018)

Back to Water: Signature of Adaptive Evolution in Cetacean Mitochondrial tRNAs
por: Montelli, Stefano, et al.
Publicado: (2016)

Mammalian NSUN2 introduces 5-methylcytidines into mitochondrial tRNAs
por: Shinoda, Saori, et al.
Publicado: (2019)

Intronic tRNAs of mitochondrial origin regulate constitutive and alternative splicing
por: Hoser, Simon M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_273rej5hv1rfp9qv89gi6hkl8v