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Lack of the effect of lobeglitazone, a peroxisome proliferator-activated receptor-γ agonist, on the pharmacokinetics and pharmacodynamics of warfarin
AIMS: Lobeglitazone has been developed for the treatment of type 2 diabetes mellitus. This study was conducted to evaluate potential drug–drug interactions between lobeglitazone and warfarin, an anticoagulant with a narrow therapeutic index. METHODS: In this open-label, three-treatment, crossover st...
Autores principales: | Jung, Jin Ah, Lee, Soo-Yun, Kim, Tae-Eun, Kim, Jung-Ryul, Kim, Chin, Huh, Wooseong, Ko, Jae-Wook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354432/ https://www.ncbi.nlm.nih.gov/pubmed/25767371 http://dx.doi.org/10.2147/DDDT.S76591 |
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