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Subacute Sclerosing Panencephalitis in a Child with Recurrent Febrile Seizures
Subacute sclerosing panencephalitis (SSPE) is a devastating disease of the central nervous system (CNS) caused by persistent mutant measles virus infection. The diagnosis of SSPE is based on characteristic clinical and EEG findings and demonstration of elevated antibody titres against measles in cer...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354718/ https://www.ncbi.nlm.nih.gov/pubmed/25802788 http://dx.doi.org/10.1155/2015/783936 |
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author | Kartal, Ayşe Çıtak Kurt, Ayşegül Neşe Hirfanoğlu, Tuğba Aydın, Kürşad Serdaroğlu, Ayşe |
author_facet | Kartal, Ayşe Çıtak Kurt, Ayşegül Neşe Hirfanoğlu, Tuğba Aydın, Kürşad Serdaroğlu, Ayşe |
author_sort | Kartal, Ayşe |
collection | PubMed |
description | Subacute sclerosing panencephalitis (SSPE) is a devastating disease of the central nervous system (CNS) caused by persistent mutant measles virus infection. The diagnosis of SSPE is based on characteristic clinical and EEG findings and demonstration of elevated antibody titres against measles in cerebrospinal fluid. Subacute sclerosing panencephalitis can have atypical clinical features at the onset. Herein, we report an unusual case of subacute sclerosing panencephalitis in a child with recurrent febrile seizures. The disease progressed with an appearance of myoclonic jerks, periodic high amplitude generalized complexes on EEG, and elevated titers of measles antibodies in cerebrospinal fluid leading to the final diagnosis of subacute sclerosing panencephalitis. |
format | Online Article Text |
id | pubmed-4354718 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-43547182015-03-23 Subacute Sclerosing Panencephalitis in a Child with Recurrent Febrile Seizures Kartal, Ayşe Çıtak Kurt, Ayşegül Neşe Hirfanoğlu, Tuğba Aydın, Kürşad Serdaroğlu, Ayşe Case Rep Pediatr Case Report Subacute sclerosing panencephalitis (SSPE) is a devastating disease of the central nervous system (CNS) caused by persistent mutant measles virus infection. The diagnosis of SSPE is based on characteristic clinical and EEG findings and demonstration of elevated antibody titres against measles in cerebrospinal fluid. Subacute sclerosing panencephalitis can have atypical clinical features at the onset. Herein, we report an unusual case of subacute sclerosing panencephalitis in a child with recurrent febrile seizures. The disease progressed with an appearance of myoclonic jerks, periodic high amplitude generalized complexes on EEG, and elevated titers of measles antibodies in cerebrospinal fluid leading to the final diagnosis of subacute sclerosing panencephalitis. Hindawi Publishing Corporation 2015 2015-02-24 /pmc/articles/PMC4354718/ /pubmed/25802788 http://dx.doi.org/10.1155/2015/783936 Text en Copyright © 2015 Ayşe Kartal et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Kartal, Ayşe Çıtak Kurt, Ayşegül Neşe Hirfanoğlu, Tuğba Aydın, Kürşad Serdaroğlu, Ayşe Subacute Sclerosing Panencephalitis in a Child with Recurrent Febrile Seizures |
title | Subacute Sclerosing Panencephalitis in a Child with Recurrent Febrile Seizures |
title_full | Subacute Sclerosing Panencephalitis in a Child with Recurrent Febrile Seizures |
title_fullStr | Subacute Sclerosing Panencephalitis in a Child with Recurrent Febrile Seizures |
title_full_unstemmed | Subacute Sclerosing Panencephalitis in a Child with Recurrent Febrile Seizures |
title_short | Subacute Sclerosing Panencephalitis in a Child with Recurrent Febrile Seizures |
title_sort | subacute sclerosing panencephalitis in a child with recurrent febrile seizures |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354718/ https://www.ncbi.nlm.nih.gov/pubmed/25802788 http://dx.doi.org/10.1155/2015/783936 |
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