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Fatty Acid Elongase 7 Catalyzes the Lipidome Remodeling Essential for Human Cytomegalovirus Replication

Human cytomegalovirus (HCMV) infection rewires host cell metabolism, up-regulating flux from glucose into acetyl-CoA to feed fatty acid metabolism, with saturated very long-chain fatty acids (VLFCA) required for production of infectious virion progeny. The human genome encodes seven elongase enzymes...

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Detalles Bibliográficos
Autores principales:	Purdy, John G., Shenk, Thomas, Rabinowitz, Joshua D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354725/ https://www.ncbi.nlm.nih.gov/pubmed/25732827 http://dx.doi.org/10.1016/j.celrep.2015.02.003

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