Cargando…
TRAP-seq defines markers for novel populations of hypothalamic and brainstem LepRb neurons
OBJECTIVE: Leptin acts via its receptor (LepRb) on multiple subpopulations of LepRb neurons in the brain, each of which controls specific aspects of energy balance. Despite the importance of LepRb-containing neurons, the transcriptome and molecular identity of many LepRb subpopulations remain undefi...
Autores principales: | Allison, Margaret B., Patterson, Christa M., Krashes, Michael J., Lowell, Bradford B., Myers, Martin G., Olson, David P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354921/ https://www.ncbi.nlm.nih.gov/pubmed/25830093 http://dx.doi.org/10.1016/j.molmet.2015.01.012 |
Ejemplares similares
-
Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neurons
por: Cady, Gillian, et al.
Publicado: (2017) -
Leptin/LepRb in the Ventral Tegmental Area Mediates Anxiety-Related Behaviors
por: Liu, Jing, et al.
Publicado: (2015) -
LepRb(+) cell–specific deletion of Slug mitigates obesity and nonalcoholic fatty liver disease in mice
por: Kim, Min-Hyun, et al.
Publicado: (2023) -
Leptin-LepRb Expressed in Gastric Cancer Patients and Related to Cancer-Related Depression
por: Pan, Yunbao, et al.
Publicado: (2017) -
Irs2 and Irs4 synergize in non-LepRb neurons to control energy balance and glucose homeostasis()
por: Sadagurski, Marianna, et al.
Publicado: (2013)