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FTO is necessary for the induction of leptin resistance by high-fat feeding

OBJECTIVE: Loss of function FTO mutations significantly impact body composition in humans and mice, with Fto-deficient mice reported to resist the development of obesity in response to a high-fat diet (HFD). We aimed to further explore the interactions between FTO and HFD and determine if FTO can in...

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Detalles Bibliográficos
Autores principales:	Tung, Y.C. Loraine, Gulati, Pawan, Liu, Che-Hsiung, Rimmington, Debra, Dennis, Rowena, Ma, Marcella, Saudek, Vladimir, O'Rahilly, Stephen, Coll, Anthony P., Yeo, Giles S.H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354923/ https://www.ncbi.nlm.nih.gov/pubmed/25830092 http://dx.doi.org/10.1016/j.molmet.2015.01.011

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