Serum progranulin levels are elevated in dermatomyositis patients with acute interstitial lung disease, predicting prognosis

INTRODUCTION: Progranulin (PGRN), a pleiotropic growth factor, has emerged as an immunoregulatory molecule. Because the roles of PGRN in dermatomyositis (DM) are still unknown, we investigated whether serum PGRN levels are associated with disease activity and prognosis in DM patients, particularly i...

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Detalles Bibliográficos
Autores principales: Tanaka, Atsushi, Tsukamoto, Hiroshi, Mitoma, Hiroki, Kiyohara, Chikako, Ueda, Naoyasu, Ayano, Masahiro, Ohta, Shun-ichiro, Kimoto, Yasutaka, Akahoshi, Mitsuteru, Arinobu, Yojiro, Niiro, Hiroaki, Tada, Yoshifumi, Horiuchi, Takahiko, Akashi, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354987/
https://www.ncbi.nlm.nih.gov/pubmed/25888887
http://dx.doi.org/10.1186/s13075-015-0547-z

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