Cargando…

Metalloprotease NleC Suppresses Host NF-κB/Inflammatory Responses by Cleaving p65 and Interfering with the p65/RPS3 Interaction

Attaching/Effacing (A/E) pathogens including enteropathogenic Escherichia coli (EPEC), enterohemorrhagic E. coli (EHEC) and the rodent equivalent Citrobacter rodentium are important causative agents of foodborne diseases. Upon infection, a myriad of virulence proteins (effectors) encoded by A/E path...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hodgson, Andrea, Wier, Eric M., Fu, Kai, Sun, Xin, Yu, Hongbing, Zheng, Wenxin, Sham, Ho Pan, Johnson, Kaitlin, Bailey, Scott, Vallance, Bruce A., Wan, Fengyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355070/ https://www.ncbi.nlm.nih.gov/pubmed/25756944 http://dx.doi.org/10.1371/journal.ppat.1004705

Ejemplares similares

NleC, a Type III Secretion Protease, Compromises NF-κB Activation by Targeting p65/RelA
por: Yen, Hilo, et al.
Publicado: (2010)

T3SS-Independent Uptake of the Short-Trip Toxin-Related Recombinant NleC Effector of Enteropathogenic Escherichia coli Leads to NF-κB p65 Cleavage
por: Stolle, Anne-Sophie, et al.
Publicado: (2017)

The T3SS Effector Protease NleC Is Active within Citrobacter rodentium
por: Hasan, Md Kamrul, et al.
Publicado: (2021)

The Apoptogenic Toxin AIP56 Is a Metalloprotease A-B Toxin that Cleaves NF-κb P65
por: Silva, Daniela S., et al.
Publicado: (2013)

Proteasome-independent Degradation of Canonical NFκB Complex Components by the NleC Protein of Pathogenic Escherichia coli
por: Mühlen, Sabrina, et al.
Publicado: (2011)

A type III effector protease NleC from enteropathogenic Escherichia coli targets NF-κB for degradation
por: Pearson, Jaclyn S, et al.
Publicado: (2011)

The Structure and Specificity of the Type III Secretion System Effector NleC Suggest a DNA Mimicry Mechanism of Substrate Recognition
por: Turco, Michelle Marian, et al.
Publicado: (2014)

The Type III Effectors NleE and NleB from Enteropathogenic E. coli and OspZ from Shigella Block Nuclear Translocation of NF-κB p65
por: Newton, Hayley J., et al.
Publicado: (2010)

Interleukin-1β triggers matrix metalloprotease-3 expression through p65/RelA activation in melanoma cells
por: Nunomura, Junichi, et al.
Publicado: (2022)

Hunting for Serine 276-Phosphorylated p65
por: Spooren, Anneleen, et al.
Publicado: (2010)

Inhibition of p65 Nuclear Translocation by Baicalein
por: Seo, Min Bum, et al.
Publicado: (2011)

The DEAD-Box RNA Helicase DDX3 Interacts with NF-κB Subunit p65 and Suppresses p65-Mediated Transcription
por: Xiang, Nian, et al.
Publicado: (2016)

Matrix Metalloprotease-7 Mediates Nucleolar Assembly and Intra-nucleolar Cleaving p53 in Gefitinib-Resistant Cancer Stem Cells
por: Yu, Wei-Hsuan, et al.
Publicado: (2020)

$\beta^{-}$ decay of $^{65}$Mn to $^{65}$Fe
por: Olaizola, B., et al.
Publicado: (2013)

Cohort Profile: The Lausanne cohort 65+ (Lc65+)
por: Henchoz, Yves, et al.
Publicado: (2021)

At SC65
por: CERN PhotoLab
Publicado: (1979)

Metadherin, p50, and p65 Expression in Epithelial Ovarian Neoplasms: An Immunohistochemical Study
por: Giopanou, Ioanna, et al.
Publicado: (2014)

Quantitative Analysis of the P65 Gene Expression in Patients with Coloroctal Cancer
por: Balcerczak, E., et al.
Publicado: (2007)

Mechanisms of NF-κB p65 and strategies for therapeutic manipulation
por: Giridharan, Sivagami, et al.
Publicado: (2018)

The Expression of SOCS and NF-ϰB p65 in Hypopharyngeal Carcinoma
por: FENG, Shu, et al.
Publicado: (2018)

Expression and Regulation of the Escherichia coli O157:H7 Effector Proteins NleH1 and NleH2
por: Holmes, Ashleigh, et al.
Publicado: (2012)

Topological data analysis gives two folding paths in HP35(nle-nle), double mutant of villin headpiece subdomain
por: Ichinomiya, Takashi
Publicado: (2022)

Members of the Fibroblast Growth Factor Receptor Superfamily Are Proteolytically Cleaved by Two Differently Activated Metalloproteases
por: Dixit, Garima, et al.
Publicado: (2021)

Identification of the polymerase polyprotein products p72 and p65 of the murine coronavirus MHV-JHM
por: Gao, Hong-Qiang, et al.
Publicado: (1996)

SPSC Meeting 65
por: Dainton, J B, et al.
Publicado: (2003)

Management Meeting No. 65
por: Reich, K H
Publicado: (1961)

Cases 27–65
por: Ahmad, Jawad
Publicado: (2010)

Census Bulletin No. 65
Publicado: (1881)

Epidermal p65/NF-κB signalling is essential for skin carcinogenesis
por: Kim, Chun, et al.
Publicado: (2014)

Increased expression of nuclear factor kappa-B p65 subunit in adenomyosis
por: Park, Hana, et al.
Publicado: (2016)

P65 Targets FGFR1 to Regulate the Survival of Ovarian Granulosa Cells
por: Yuan, Xiaolong, et al.
Publicado: (2019)

p65BTK Is a Novel Biomarker and Therapeutic Target in Solid Tumors
por: Grassilli, Emanuela, et al.
Publicado: (2021)

Parkin drives pS65‐Ub turnover independently of canonical autophagy in Drosophila
por: Usher, Joanne L, et al.
Publicado: (2022)

Fe65-PTB2 Dimerization Mimics Fe65-APP Interaction
por: Feilen, Lukas P., et al.
Publicado: (2017)

Multilevel ecological analysis of the predictors of spanking across 65 countries
por: Ward, Kaitlin Paxton, et al.
Publicado: (2021)

Cautionary notes on the use of NF-κB p65 and p50 antibodies for CNS studies
por: Herkenham, Miles, et al.
Publicado: (2011)

Acetylation of p65(Lys310) by p300 in macrophages mediates anti-inflammatory property of berberine
por: Zhang, Shuchen, et al.
Publicado: (2023)

Two Modes of Transcriptional Activation at Native Promoters by NF-κB p65
por: van Essen, Dominic, et al.
Publicado: (2009)

Regulation of GAD65 expression by SMAR1 and p53 upon Streptozotocin treatment
por: Singh, Sandeep, et al.
Publicado: (2012)

NF-κB p65 directs sex-specific neuroprotection in human neurons
por: Ruiz-Perera, Lucia M., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_hr0ejnjr49qtltmd5fmkavqqef