Cargando…

Orostachys japonicus Inhibits Expression of the TLR4, NOD2, iNOS, and COX-2 Genes in LPS-Stimulated Human PMA-Differentiated THP-1 Cells by Inhibiting NF-κB and MAPK Activation

Orostachys japonicus is traditionally used as an inflammatory agent. In this report, we investigated the effects of O. japonicus extract on the expression of genes encoding pathogen-recognition receptors (TLR2, TLR4, NOD1, and NOD2) and proinflammatory factors (iNOS, COX-2, and cytokines) in LPS-sti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yoon, Yeo-Kwang, Woo, Hong-Jung, Kim, Youngchul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355124/ https://www.ncbi.nlm.nih.gov/pubmed/25810745 http://dx.doi.org/10.1155/2015/682019

Ejemplares similares

Orostachys japonicus extract inhibits the lipopolysaccharide‐induced pro‐inflammatory factors by suppression of transcription factors
por: Lee, Hyeong‐Seon
Publicado: (2020)

Dataset on the differentiation of THP-1 monocytes to LPS inducible adherent macrophages and their capacity for NO/iNOS signaling
por: Ozleyen, Adem, et al.
Publicado: (2021)

Luteolin, a bioflavonoid inhibits azoxymethane-induced colon carcinogenesis: Involvement of iNOS and COX-2
por: Pandurangan, Ashok Kumar, et al.
Publicado: (2014)

Subcritical water extraction of bioactive compounds from Orostachys japonicus A. Berger (Crassulaceae)
por: Ko, Min-Jung, et al.
Publicado: (2020)

Leishmania mexicana promastigotes inhibit macrophage IL-12 production via TLR-4 dependent COX-2, iNOS and arginase-1 expression
por: Shweash, Muhannad, et al.
Publicado: (2011)

Ginsenoside Rd inhibits the expressions of iNOS and COX-2 by suppressing NF-κB in LPS-stimulated RAW264.7 cells and mouse liver
por: Kim, Dae Hyun, et al.
Publicado: (2013)

The effect of systemic iNOS inhibition during human endotoxemia on the development of TLR-tolerance in vitro
por: Pickkers, P, et al.
Publicado: (2006)

Obesity-Induced Coronary Microvascular Disease Is Prevented by iNOS Deletion and Reversed by iNOS Inhibition
por: Shah, Soham A., et al.
Publicado: (2023)

Carfilzomib inhibits the proliferation and apoptosis of multiple myeloma cells by inhibiting STAT1/COX-2/iNOS signaling pathway
por: He, Shaolong, et al.
Publicado: (2022)

Hypolipidemic and hypoglycemic effects of Orostachys japonicus A. Berger extracts in streptozotocin-induced diabetic rats
por: Lee, Soo Jung, et al.
Publicado: (2011)

Dietary Blue Pigments Derived from Genipin, Attenuate Inflammation by Inhibiting LPS-Induced iNOS and COX-2 Expression via the NF-κB Inactivation
por: Wang, Qiang-Song, et al.
Publicado: (2012)

Pseudane-VII Regulates LPS-Induced Neuroinflammation in Brain Microglia Cells through the Inhibition of iNOS Expression
por: Kim, Mi Eun, et al.
Publicado: (2018)

Quercetin inhibits LPS-induced macrophage migration by suppressing the iNOS/FAK/paxillin pathway and modulating the cytoskeleton
por: Cui, Shuna, et al.
Publicado: (2018)

High Glucose Induces Endothelial COX2 and iNOS Expression via Inhibition of Monomethyltransferase SETD8 Expression
por: Qi, Jie, et al.
Publicado: (2020)

Red Ginseng Marc Oil Inhibits iNOS and COX-2 via NFκB and p38 Pathways in LPS-Stimulated RAW 264.7 Macrophages
por: Bak, Min-Ji, et al.
Publicado: (2012)

Daphne jejudoensis Attenuates LPS-Induced Inflammation by Inhibiting TNF-α, IL-1β, IL-6, iNOS, and COX-2 Expression in Periodontal Ligament Cells
por: Bae, Ji-Yeong, et al.
Publicado: (2022)

Brain function in iNOS knock out or iNOS inhibited (l-NIL) mice under endotoxic shock
por: Schweighöfer, Hanna, et al.
Publicado: (2014)

Orostachys japonicus A. Berger Extracts Induce Immunity-Enhancing Effects on Cyclophosphamide-Treated Immunosuppressed Rats
por: Lee, Hak Yong, et al.
Publicado: (2019)

Discovery of Phenolic Glycoside from Hyssopus cuspidatus Attenuates LPS-Induced Inflammatory Responses by Inhibition of iNOS and COX-2 Expression through Suppression of NF-κB Activation
por: Liu, Xingyu, et al.
Publicado: (2021)

Flavonoids from Orostachys japonicus A. Berger Inhibit the Invasion of LnCaP Prostate Carcinoma Cells by Inactivating Akt and Modulating Tight Junctions
por: Shin, Dong Yeok, et al.
Publicado: (2013)

Inhibition of Inflammation and iNOS Improves Lymphatic Function in Obesity
por: Torrisi, Jeremy S., et al.
Publicado: (2016)

Leaves of Raphanus sativus L. Shows Anti-Inflammatory Activity in LPS-Stimulated Macrophages via Suppression of COX-2 and iNOS Expression
por: Park, Hye-Jin, et al.
Publicado: (2017)

Analysis of metabolomic profile of fermented Orostachys japonicus A. Berger by capillary electrophoresis time of flight mass spectrometry
por: Das, Gitishree, et al.
Publicado: (2017)

Anti-oxidizing effect of the dichloromethane and hexane fractions from Orostachys japonicus in LPS-stimulated RAW 264.7 cells via upregulation of Nrf2 expression and activation of MAPK signaling pathway
por: Lee, Hyeong-Seon, et al.
Publicado: (2014)

Antioxidative effects of cinnamomi cortex: A potential role of iNOS and COX-II
por: Chung, Jin-Won, et al.
Publicado: (2011)

Butanol extracts of Asparagus cochinchinensis fermented with Weissella cibaria inhibit iNOS-mediated COX-2 induction pathway and inflammatory cytokines in LPS-stimulated RAW264.7 macrophage cells
por: Lee, Hyun Ah, et al.
Publicado: (2017)

Cox-2 Inhibition Protects against Hypoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis via Akt-Dependent Enhancement of iNOS Expression
por: Pang, Lei, et al.
Publicado: (2016)

Perthamide C Inhibits eNOS and iNOS Expression and Has Immunomodulating Activity In Vivo
por: Bucci, Mariarosaria, et al.
Publicado: (2013)

Anti-fibrotic effects of Orostachys japonicus A. Berger (Crassulaceae) on hepatic stellate cells and thioacetamide-induced fibrosis in rats
por: Koppula, Sushruta, et al.
Publicado: (2017)

Orostachys japonicus exerts antipancreatic cancer activity through induction of apoptosis and cell cycle arrest in PANC‐1 cells
por: Kim, Ji Hyun, et al.
Publicado: (2019)

Therapeutic effects of iNOS inhibition against vitiligo in an animal model
por: Mansourpour, Hamid, et al.
Publicado: (2019)

Amphiregulin Induces iNOS and COX-2 Expression through NF-κB and MAPK Signaling in Hepatic Inflammation
por: Heo, Yu Jung, et al.
Publicado: (2023)

Melatonin Enhances the Anti-Tumor Effect of Fisetin by Inhibiting COX-2/iNOS and NF-κB/p300 Signaling Pathways
por: Yi, Canhui, et al.
Publicado: (2014)

Maprotiline inhibits COX2 and iNOS gene expression in lipopolysaccharide-stimulated U937 macrophages and carrageenan-induced paw edema in rats
por: Rafiee, Laleh, et al.
Publicado: (2019)

Retraction: Perthamide C Inhibits eNOS and iNOS Expression and Has Immunomodulating Activity In Vivo
Publicado: (2019)

Inhibition of LPS-Induced Oxidative Damages and Potential Anti-Inflammatory Effects of Phyllanthus emblica Extract via Down-Regulating NF-κB, COX-2, and iNOS in RAW 264.7 Cells
por: Wang, Hui Min-David, et al.
Publicado: (2019)

Optimization of differentiation and transcriptomic profile of THP-1 cells into macrophage by PMA
por: Liu, Tiezhu, et al.
Publicado: (2023)

Propolis Exerts an Anti-Inflammatory Effect on PMA-Differentiated THP-1 Cells via Inhibition of Purine Nucleoside Phosphorylase
por: Alqarni, Abdulmalik M., et al.
Publicado: (2019)

Orostachys japonicus induce p53‐dependent cell cycle arrest through the MAPK signaling pathway in OVCAR‐3 human ovarian cancer cells
por: Lee, Kyung‐Sun, et al.
Publicado: (2018)

Effect of iNOS inhibition on exhaled NO and serum nitrate in hyperdynamic porcine endotoxemia
por: Theisen, MM, et al.
Publicado: (2000)

Cannot write session to /tmp/vufind_sessions/sess_qurduq3ti5f56sjr5ea9n58gqv