Spectacle: fast chromatin state annotation using spectral learning

Epigenomic data from ENCODE can be used to associate specific combinations of chromatin marks with regulatory elements in the human genome. Hidden Markov models and the expectation-maximization (EM) algorithm are often used to analyze epigenomic data. However, the EM algorithm can have overfitting p...

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Detalles Bibliográficos
Autores principales: Song, Jimin, Chen, Kevin C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355146/
https://www.ncbi.nlm.nih.gov/pubmed/25786205
http://dx.doi.org/10.1186/s13059-015-0598-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355146/
https://www.ncbi.nlm.nih.gov/pubmed/25786205
http://dx.doi.org/10.1186/s13059-015-0598-0

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