Identification of the Base-Pairing Requirements for Repression of hctA Translation by the Small RNA IhtA Leads to the Discovery of a New mRNA Target in Chlamydia trachomatis

The non-coding small RNA, IhtA expressed by the obligate intracellular human pathogen Chlamydia trachomatis modulates the translation of HctA, a key protein involved in replicative to infectious cell type differentiation. Using a combination of bioinformatics and mutagenesis we sought to identify th...

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Detalles Bibliográficos
Autores principales: Grieshaber, Nicole A., Tattersall, Jeremiah S., Liguori, Johella, Lipat, Joseph N., Runac, Justin, Grieshaber, Scott S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355289/
https://www.ncbi.nlm.nih.gov/pubmed/25756658
http://dx.doi.org/10.1371/journal.pone.0116593

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