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T-cell reprogramming through targeted CD4-coreceptor and T-cell receptor expression on maturing thymocytes by latent Circoviridae family member porcine circovirus type 2 cell infections in the thymus
Although porcine circovirus type 2 (PCV2)-associated diseases have been evaluated for known immune evasion strategies, the pathogenicity of these viruses remained concealed for decades. Surprisingly, the same viruses that cause panzootics in livestock are widespread in young, unaffected animals. Rec...
Autores principales: | Klausmann, Stefanie, Sydler, Titus, Summerfield, Artur, Lewis, Fraser I, Weilenmann, Roseline, Sidler, Xaver, Brugnera, Enrico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355439/ https://www.ncbi.nlm.nih.gov/pubmed/26038767 http://dx.doi.org/10.1038/emi.2015.15 |
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