Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro Fertilization

Drug-induced immune thrombocytopenia has been associated with hundreds of medications and can lead to devastating consequences for the patient. We present a case of a healthy 33-year-old female undergoing in vitro fertilization who developed a severe drug-induced thrombocytopenia, petechiae, and a l...

Descripción completa

Detalles Bibliográficos
Autores principales: Comstock, Ioanna A., Longmire, Michelle, Aster, Richard H., Milki, Amin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355607/
https://www.ncbi.nlm.nih.gov/pubmed/25810935
http://dx.doi.org/10.1155/2015/890610
_version_ 1782360886621503488
author Comstock, Ioanna A.
Longmire, Michelle
Aster, Richard H.
Milki, Amin A.
author_facet Comstock, Ioanna A.
Longmire, Michelle
Aster, Richard H.
Milki, Amin A.
author_sort Comstock, Ioanna A.
collection PubMed
description Drug-induced immune thrombocytopenia has been associated with hundreds of medications and can lead to devastating consequences for the patient. We present a case of a healthy 33-year-old female undergoing in vitro fertilization who developed a severe drug-induced thrombocytopenia, petechiae, and a large hemoperitoneum after receiving Cefazolin antibiotic prophylaxis for a transvaginal oocyte retrieval. The patient was admitted to the intensive care unit for resuscitation with blood products. The presence of drug-dependent platelet antibodies to Cefazolin was confirmed serologically.
format Online
Article
Text
id pubmed-4355607
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-43556072015-03-25 Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro Fertilization Comstock, Ioanna A. Longmire, Michelle Aster, Richard H. Milki, Amin A. Case Rep Obstet Gynecol Case Report Drug-induced immune thrombocytopenia has been associated with hundreds of medications and can lead to devastating consequences for the patient. We present a case of a healthy 33-year-old female undergoing in vitro fertilization who developed a severe drug-induced thrombocytopenia, petechiae, and a large hemoperitoneum after receiving Cefazolin antibiotic prophylaxis for a transvaginal oocyte retrieval. The patient was admitted to the intensive care unit for resuscitation with blood products. The presence of drug-dependent platelet antibodies to Cefazolin was confirmed serologically. Hindawi Publishing Corporation 2015 2015-02-25 /pmc/articles/PMC4355607/ /pubmed/25810935 http://dx.doi.org/10.1155/2015/890610 Text en Copyright © 2015 Ioanna A. Comstock et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Comstock, Ioanna A.
Longmire, Michelle
Aster, Richard H.
Milki, Amin A.
Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro Fertilization
title Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro Fertilization
title_full Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro Fertilization
title_fullStr Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro Fertilization
title_full_unstemmed Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro Fertilization
title_short Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro Fertilization
title_sort drug-induced thrombocytopenia following a transvaginal oocyte retrieval for in vitro fertilization
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355607/
https://www.ncbi.nlm.nih.gov/pubmed/25810935
http://dx.doi.org/10.1155/2015/890610
work_keys_str_mv AT comstockioannaa druginducedthrombocytopeniafollowingatransvaginaloocyteretrievalforinvitrofertilization
AT longmiremichelle druginducedthrombocytopeniafollowingatransvaginaloocyteretrievalforinvitrofertilization
AT asterrichardh druginducedthrombocytopeniafollowingatransvaginaloocyteretrievalforinvitrofertilization
AT milkiamina druginducedthrombocytopeniafollowingatransvaginaloocyteretrievalforinvitrofertilization

Ejemplares similares