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DivStat: A User-Friendly Tool for Single Nucleotide Polymorphism Analysis of Genomic Diversity
Recent developments have led to an enormous increase of publicly available large genomic data, including complete genomes. The 1000 Genomes Project was a major contributor, releasing the results of sequencing a large number of individual genomes, and allowing for a myriad of large scale studies on h...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355611/ https://www.ncbi.nlm.nih.gov/pubmed/25756185 http://dx.doi.org/10.1371/journal.pone.0119851 |
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author | Soares, Inês Moleirinho, Ana Oliveira, Gonçalo N. P. Amorim, António |
author_facet | Soares, Inês Moleirinho, Ana Oliveira, Gonçalo N. P. Amorim, António |
author_sort | Soares, Inês |
collection | PubMed |
description | Recent developments have led to an enormous increase of publicly available large genomic data, including complete genomes. The 1000 Genomes Project was a major contributor, releasing the results of sequencing a large number of individual genomes, and allowing for a myriad of large scale studies on human genetic variation. However, the tools currently available are insufficient when the goal concerns some analyses of data sets encompassing more than hundreds of base pairs and when considering haplotype sequences of single nucleotide polymorphisms (SNPs). Here, we present a new and potent tool to deal with large data sets allowing the computation of a variety of summary statistics of population genetic data, increasing the speed of data analysis. |
format | Online Article Text |
id | pubmed-4355611 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-43556112015-03-17 DivStat: A User-Friendly Tool for Single Nucleotide Polymorphism Analysis of Genomic Diversity Soares, Inês Moleirinho, Ana Oliveira, Gonçalo N. P. Amorim, António PLoS One Research Article Recent developments have led to an enormous increase of publicly available large genomic data, including complete genomes. The 1000 Genomes Project was a major contributor, releasing the results of sequencing a large number of individual genomes, and allowing for a myriad of large scale studies on human genetic variation. However, the tools currently available are insufficient when the goal concerns some analyses of data sets encompassing more than hundreds of base pairs and when considering haplotype sequences of single nucleotide polymorphisms (SNPs). Here, we present a new and potent tool to deal with large data sets allowing the computation of a variety of summary statistics of population genetic data, increasing the speed of data analysis. Public Library of Science 2015-03-10 /pmc/articles/PMC4355611/ /pubmed/25756185 http://dx.doi.org/10.1371/journal.pone.0119851 Text en © 2015 Soares et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Soares, Inês Moleirinho, Ana Oliveira, Gonçalo N. P. Amorim, António DivStat: A User-Friendly Tool for Single Nucleotide Polymorphism Analysis of Genomic Diversity |
title | DivStat: A User-Friendly Tool for Single Nucleotide Polymorphism Analysis of Genomic Diversity |
title_full | DivStat: A User-Friendly Tool for Single Nucleotide Polymorphism Analysis of Genomic Diversity |
title_fullStr | DivStat: A User-Friendly Tool for Single Nucleotide Polymorphism Analysis of Genomic Diversity |
title_full_unstemmed | DivStat: A User-Friendly Tool for Single Nucleotide Polymorphism Analysis of Genomic Diversity |
title_short | DivStat: A User-Friendly Tool for Single Nucleotide Polymorphism Analysis of Genomic Diversity |
title_sort | divstat: a user-friendly tool for single nucleotide polymorphism analysis of genomic diversity |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355611/ https://www.ncbi.nlm.nih.gov/pubmed/25756185 http://dx.doi.org/10.1371/journal.pone.0119851 |
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