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Angiostatic treatment prior to chemo- or photodynamic therapy improves anti-tumor efficacy
Tumor vasculature is known to be poorly organized leading to increased leakage of molecules to the extravascular space. This process can potentially increase interstitial fluid pressure impairing intra-tumoral blood flow and oxygen supply, and can affect drug uptake. Anti-angiogenic therapies are be...
Autores principales: | Weiss, Andrea, Bonvin, Débora, Berndsen, Robert H., Scherrer, Edoardo, Wong, Tse J., Dyson, Paul J., Griffioen, Arjan W., Nowak-Sliwinska, Patrycja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355632/ https://www.ncbi.nlm.nih.gov/pubmed/25758612 http://dx.doi.org/10.1038/srep08990 |
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