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In vitro Antioxidant Potential in Sequential Extracts of Curcuma caesia Roxb. Rhizomes

Present study deals with antioxidant potential of sequential extracts of fresh and dried rhizomes of Curcuma caesia, using solvents viz., hexane, petroleum ether, benzene, chloroform, ethyl acetate, methanol and water, which was analyzed by 2,2-diphenyl-1-picrylhydrazyl radical scavenging assay, tot...

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Autores principales: Reenu, J., Azeez, Shamina, Bhageerathy, Chempakam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355881/
https://www.ncbi.nlm.nih.gov/pubmed/25767317
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author Reenu, J.
Azeez, Shamina
Bhageerathy, Chempakam
author_facet Reenu, J.
Azeez, Shamina
Bhageerathy, Chempakam
author_sort Reenu, J.
collection PubMed
description Present study deals with antioxidant potential of sequential extracts of fresh and dried rhizomes of Curcuma caesia, using solvents viz., hexane, petroleum ether, benzene, chloroform, ethyl acetate, methanol and water, which was analyzed by 2,2-diphenyl-1-picrylhydrazyl radical scavenging assay, total antioxidant capacity, ferric reducing activity and thiobarbituric acid reactive species assay. Total phenol content was estimated by the Folin-Ciocalteau method. C. caesia showed significant antioxidant activity in chloroform, benzene and ethyl acetate extracts. The chloroform extract was highly effective as free radical scavengers, electron-donating agents and reducing molybdate ions except for reducing lipid peroxidation. The highest total phenol content was also exhibited by chloroform and benzene extracts. Antioxidant potential expressed by C. caesia in the sequential extracts could be effectively utilized for identification of the bioactive compounds for future phytopharmacological applications.
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spelling pubmed-43558812015-03-12 In vitro Antioxidant Potential in Sequential Extracts of Curcuma caesia Roxb. Rhizomes Reenu, J. Azeez, Shamina Bhageerathy, Chempakam Indian J Pharm Sci Research Paper Present study deals with antioxidant potential of sequential extracts of fresh and dried rhizomes of Curcuma caesia, using solvents viz., hexane, petroleum ether, benzene, chloroform, ethyl acetate, methanol and water, which was analyzed by 2,2-diphenyl-1-picrylhydrazyl radical scavenging assay, total antioxidant capacity, ferric reducing activity and thiobarbituric acid reactive species assay. Total phenol content was estimated by the Folin-Ciocalteau method. C. caesia showed significant antioxidant activity in chloroform, benzene and ethyl acetate extracts. The chloroform extract was highly effective as free radical scavengers, electron-donating agents and reducing molybdate ions except for reducing lipid peroxidation. The highest total phenol content was also exhibited by chloroform and benzene extracts. Antioxidant potential expressed by C. caesia in the sequential extracts could be effectively utilized for identification of the bioactive compounds for future phytopharmacological applications. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4355881/ /pubmed/25767317 Text en Copyright: © Indian Journal of Pharmaceutical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Paper
Reenu, J.
Azeez, Shamina
Bhageerathy, Chempakam
In vitro Antioxidant Potential in Sequential Extracts of Curcuma caesia Roxb. Rhizomes
title In vitro Antioxidant Potential in Sequential Extracts of Curcuma caesia Roxb. Rhizomes
title_full In vitro Antioxidant Potential in Sequential Extracts of Curcuma caesia Roxb. Rhizomes
title_fullStr In vitro Antioxidant Potential in Sequential Extracts of Curcuma caesia Roxb. Rhizomes
title_full_unstemmed In vitro Antioxidant Potential in Sequential Extracts of Curcuma caesia Roxb. Rhizomes
title_short In vitro Antioxidant Potential in Sequential Extracts of Curcuma caesia Roxb. Rhizomes
title_sort in vitro antioxidant potential in sequential extracts of curcuma caesia roxb. rhizomes
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355881/
https://www.ncbi.nlm.nih.gov/pubmed/25767317
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