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PAT1 inversely regulates the surface Amyloid Precursor Protein level in mouse primary neurons

BACKGROUND: The amyloid precursor protein (APP) is a key molecule in Alzheimer disease. Its localization at the cell surface can trigger downstream signaling and APP cleavages. APP trafficking to the cell surface in neurons is not clearly understood and may be related to the interactions with its pa...

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Detalles Bibliográficos
Autores principales:	Dilsizoglu Senol, Aysegul, Tagliafierro, Lidia, Huguet, Léa, Gorisse-Hussonnois, Lucie, Chasseigneaux, Stéphanie, Allinquant, Bernadette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355975/ https://www.ncbi.nlm.nih.gov/pubmed/25880931 http://dx.doi.org/10.1186/s12868-015-0152-8

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