Loss of periostin/OSF-2 in ErbB2/Neu-driven tumors results in androgen receptor-positive molecular apocrine-like tumors with reduced Notch1 activity

INTRODUCTION: Periostin (Postn) is a secreted cell adhesion protein that activates signaling pathways to promote cancer cell survival, angiogenesis, invasion, and metastasis. Interestingly, Postn is frequently overexpressed in numerous human cancers, including breast, lung, colon, pancreatic, and ov...

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Detalles Bibliográficos
Autores principales: Sriram, Roshan, Lo, Vivian, Pryce, Benjamin, Antonova, Lilia, Mears, Alan J, Daneshmand, Manijeh, McKay, Bruce, Conway, Simon J, Muller, William J, Sabourin, Luc A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355979/
https://www.ncbi.nlm.nih.gov/pubmed/25592291
http://dx.doi.org/10.1186/s13058-014-0513-8

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