Genome-wide DNA methylation analysis reveals estrogen-mediated epigenetic repression of metallothionein-1 gene cluster in breast cancer

BACKGROUND: Recent genome-wide analysis has shown that DNA methylation spans long stretches of chromosome regions consisting of clusters of contiguous CpG islands or gene families. Hypermethylation of various gene clusters has been reported in many types of cancer. In this study, we conducted methyl...

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Detalles Bibliográficos
Autores principales: Jadhav, Rohit R, Ye, Zhenqing, Huang, Rui-Lan, Liu, Joseph, Hsu, Pei-Yin, Huang, Yi-Wen, Rangel, Leticia B, Lai, Hung-Cheng, Roa, Juan Carlos, Kirma, Nameer B, Huang, Tim Hui-Ming, Jin, Victor X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355986/
https://www.ncbi.nlm.nih.gov/pubmed/25763113
http://dx.doi.org/10.1186/s13148-015-0045-9

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