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Direct Comparison of Linear and Macrocyclic Compound Libraries as a Source of Protein Ligands
[Image: see text] There has been much discussion of the potential desirability of macrocyclic molecules for the development of tool compounds and drug leads. But there is little experimental data comparing otherwise equivalent macrocyclic and linear compound libraries as a source of protein ligands....
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356041/ https://www.ncbi.nlm.nih.gov/pubmed/25623285 http://dx.doi.org/10.1021/co500161c |