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Hypoxia inducible factor signaling and experimental persistent pulmonary hypertension of the newborn

Background: Mitochondrial reactive oxygen species (ROS) levels and nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) activity are increased in a lamb model of persistent pulmonary hypertension of the newborn (PPHN). These events can trigger hypoxia inducible factor (HIF) signalin...

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Detalles Bibliográficos
Autores principales:	Wedgwood, Stephen, Lakshminrusimha, Satyan, Schumacker, Paul T., Steinhorn, Robin H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356070/ https://www.ncbi.nlm.nih.gov/pubmed/25814954 http://dx.doi.org/10.3389/fphar.2015.00047

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