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FGF14 modulates resurgent sodium current in mouse cerebellar Purkinje neurons

Rapid firing of cerebellar Purkinje neurons is facilitated in part by a voltage-gated Na(+) (Na(V)) ‘resurgent’ current, which allows renewed Na(+) influx during membrane repolarization. Resurgent current results from unbinding of a blocking particle that competes with normal channel inactivation. T...

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Detalles Bibliográficos
Autores principales:	Yan, Haidun, Pablo, Juan L, Wang, Chaojian, Pitt, Geoffrey S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356139/ https://www.ncbi.nlm.nih.gov/pubmed/25269146 http://dx.doi.org/10.7554/eLife.04193

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