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Added value of whole-genome sequencing for management of highly drug-resistant TB

OBJECTIVES: Phenotypic drug susceptibility testing (DST) for Mycobacterium tuberculosis takes several weeks to complete and second-line DST is often poorly reproducible, potentially leading to compromised clinical decisions. Following a fatal case of XDR TB, we investigated the potential benefit of...

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Detalles Bibliográficos
Autores principales: Outhred, Alexander C., Jelfs, Peter, Suliman, Basel, Hill-Cawthorne, Grant A., Crawford, Archibald B. H., Marais, Ben J., Sintchenko, Vitali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356205/
https://www.ncbi.nlm.nih.gov/pubmed/25492392
http://dx.doi.org/10.1093/jac/dku508