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Response to nab-paclitaxel and nedaplatin in a heavily-metastatic thymic carcinoma: A case report
Metastatic thymic carcinoma is an aggressive cancer that usually responds poorly to multimodal therapies. Although surgical resection is the preferred treatment for patients with advanced or metastatic disease, the clinical prognosis is typically poor. The present study describes a 63-year-old patie...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356389/ https://www.ncbi.nlm.nih.gov/pubmed/25789028 http://dx.doi.org/10.3892/ol.2015.2953 |
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author | ZHAN, PING XIE, HAIYAN YU, LI-KE |
author_facet | ZHAN, PING XIE, HAIYAN YU, LI-KE |
author_sort | ZHAN, PING |
collection | PubMed |
description | Metastatic thymic carcinoma is an aggressive cancer that usually responds poorly to multimodal therapies. Although surgical resection is the preferred treatment for patients with advanced or metastatic disease, the clinical prognosis is typically poor. The present study describes a 63-year-old patient with thymic carcinoma who underwent a range of antitumor treatments, including surgical resection, post-operative radiotherapy and post-operative chemotherapy with several drugs, but ultimately responded to treatment with nab-paclitaxel (nab-P) and nedaplatin. Subsequent to six cycles of nab-P and nedaplatin, the lung and peritoneal metastases decreased in size and the pleural effusion was reduced. To the best of our knowledge, this is the first study to describe the response of an advanced thymic carcinoma to nab-P chemotherapy. |
format | Online Article Text |
id | pubmed-4356389 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-43563892015-03-18 Response to nab-paclitaxel and nedaplatin in a heavily-metastatic thymic carcinoma: A case report ZHAN, PING XIE, HAIYAN YU, LI-KE Oncol Lett Articles Metastatic thymic carcinoma is an aggressive cancer that usually responds poorly to multimodal therapies. Although surgical resection is the preferred treatment for patients with advanced or metastatic disease, the clinical prognosis is typically poor. The present study describes a 63-year-old patient with thymic carcinoma who underwent a range of antitumor treatments, including surgical resection, post-operative radiotherapy and post-operative chemotherapy with several drugs, but ultimately responded to treatment with nab-paclitaxel (nab-P) and nedaplatin. Subsequent to six cycles of nab-P and nedaplatin, the lung and peritoneal metastases decreased in size and the pleural effusion was reduced. To the best of our knowledge, this is the first study to describe the response of an advanced thymic carcinoma to nab-P chemotherapy. D.A. Spandidos 2015-04 2015-02-10 /pmc/articles/PMC4356389/ /pubmed/25789028 http://dx.doi.org/10.3892/ol.2015.2953 Text en Copyright © 2015, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Articles ZHAN, PING XIE, HAIYAN YU, LI-KE Response to nab-paclitaxel and nedaplatin in a heavily-metastatic thymic carcinoma: A case report |
title | Response to nab-paclitaxel and nedaplatin in a heavily-metastatic thymic carcinoma: A case report |
title_full | Response to nab-paclitaxel and nedaplatin in a heavily-metastatic thymic carcinoma: A case report |
title_fullStr | Response to nab-paclitaxel and nedaplatin in a heavily-metastatic thymic carcinoma: A case report |
title_full_unstemmed | Response to nab-paclitaxel and nedaplatin in a heavily-metastatic thymic carcinoma: A case report |
title_short | Response to nab-paclitaxel and nedaplatin in a heavily-metastatic thymic carcinoma: A case report |
title_sort | response to nab-paclitaxel and nedaplatin in a heavily-metastatic thymic carcinoma: a case report |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356389/ https://www.ncbi.nlm.nih.gov/pubmed/25789028 http://dx.doi.org/10.3892/ol.2015.2953 |
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