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A let-7b binding site SNP in the 3′-UTR of the Bcl-xL gene enhances resistance to 5-fluorouracil and doxorubicin in breast cancer cells

The development of acquired resistance to chemotherapy is a major obstacle in the successful treatment of cancer. In breast cancer cells, B-cell lymphoma-extra large (Bcl-xL) is involved in the development of resistance to various chemotherapeutic agents; therefore, preliminary biological prediction...

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Detalles Bibliográficos
Autores principales:	WANG, TING, HUANG, BIN, GUO, RUI, MA, JIN, PENG, CUIYING, ZU, XUYU, TANG, HUIFANG, LEI, XIAOYONG
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356428/ https://www.ncbi.nlm.nih.gov/pubmed/25789066 http://dx.doi.org/10.3892/ol.2015.2938

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