A Comprehensive Library of Familial Human Amyotrophic Lateral Sclerosis Induced Pluripotent Stem Cells

Amyotrophic lateral sclerosis is a progressive disease characterized by the loss of upper and lower motor neurons, leading to paralysis of voluntary muscles. About 10% of all ALS cases are familial (fALS), among which 15–20% are linked to Cu/Zn superoxide dismutase (SOD1) mutations, usually inherite...

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Detalles Bibliográficos
Autores principales: Li, Ying, Balasubramanian, Umamahesw, Cohen, Devon, Zhang, Ping-Wu, Mosmiller, Elizabeth, Sattler, Rita, Maragakis, Nicholas J., Rothstein, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356618/
https://www.ncbi.nlm.nih.gov/pubmed/25760436
http://dx.doi.org/10.1371/journal.pone.0118266

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