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Risk factors for chronic obstructive pulmonary disease among never-smokers in Korea
BACKGROUND: Chronic obstructive pulmonary disease (COPD) patients include those who have never smoked. However, risk factors other than smoking in never-smokers have not been elucidated sufficiently. This study investigated the risk factors for COPD among never-smokers in Korea using population-base...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356706/ https://www.ncbi.nlm.nih.gov/pubmed/25784796 http://dx.doi.org/10.2147/COPD.S77662 |
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author | Lee, Seok Jeong Kim, Seo Woo Kong, Kyoung Ae Ryu, Yon Ju Lee, Jin Hwa Chang, Jung Hyun |
author_facet | Lee, Seok Jeong Kim, Seo Woo Kong, Kyoung Ae Ryu, Yon Ju Lee, Jin Hwa Chang, Jung Hyun |
author_sort | Lee, Seok Jeong |
collection | PubMed |
description | BACKGROUND: Chronic obstructive pulmonary disease (COPD) patients include those who have never smoked. However, risk factors other than smoking in never-smokers have not been elucidated sufficiently. This study investigated the risk factors for COPD among never-smokers in Korea using population-based data. METHODS: The data were retrieved from the Korean National Health and Nutrition Survey IV conducted from 2007 to 2009. Among subjects aged 40 years or older who underwent appropriate pulmonary function tests, never-smokers not diagnosed with asthma and not showing a restrictive pattern on pulmonary function tests were enrolled. Risk factors of COPD in never-smokers were analyzed using logistic regression models. RESULTS: Among 24,871 participants in the representative Korean cohort, 3,473 never-smokers were enrolled. COPD patients accounted for 7.6% of the never-smokers. In the logistic regression analysis, low education status (odds ratio [OR]: 2.0; 95% confidence interval [CI]: 1.2–3.2), occupational exposure (OR: 2.6; 95% CI: 1.3–5.3), a history of tuberculosis (OR: 4.5; 95% CI: 2.3–8.7), bronchiectasis (OR: 6.0; 95% CI: 1.4–25.4), male sex (OR: 4.2; 95% CI: 2.6–6.7), advanced age (60–69 years vs 40–49 years; OR: 3.8; 95% CI: 2.0–7.0), and being underweight (body mass index <18.5 vs 18.0–24.9 kg/m(2); OR: 3.1; 95% CI: 1.0–9.4) were associated with the development of COPD. CONCLUSION: Low education status, manual labor, a history of tuberculosis and bronchiectasis, as well as male sex, advanced age and being underweight were risk factors for COPD in Korean never-smokers. |
format | Online Article Text |
id | pubmed-4356706 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-43567062015-03-17 Risk factors for chronic obstructive pulmonary disease among never-smokers in Korea Lee, Seok Jeong Kim, Seo Woo Kong, Kyoung Ae Ryu, Yon Ju Lee, Jin Hwa Chang, Jung Hyun Int J Chron Obstruct Pulmon Dis Original Research BACKGROUND: Chronic obstructive pulmonary disease (COPD) patients include those who have never smoked. However, risk factors other than smoking in never-smokers have not been elucidated sufficiently. This study investigated the risk factors for COPD among never-smokers in Korea using population-based data. METHODS: The data were retrieved from the Korean National Health and Nutrition Survey IV conducted from 2007 to 2009. Among subjects aged 40 years or older who underwent appropriate pulmonary function tests, never-smokers not diagnosed with asthma and not showing a restrictive pattern on pulmonary function tests were enrolled. Risk factors of COPD in never-smokers were analyzed using logistic regression models. RESULTS: Among 24,871 participants in the representative Korean cohort, 3,473 never-smokers were enrolled. COPD patients accounted for 7.6% of the never-smokers. In the logistic regression analysis, low education status (odds ratio [OR]: 2.0; 95% confidence interval [CI]: 1.2–3.2), occupational exposure (OR: 2.6; 95% CI: 1.3–5.3), a history of tuberculosis (OR: 4.5; 95% CI: 2.3–8.7), bronchiectasis (OR: 6.0; 95% CI: 1.4–25.4), male sex (OR: 4.2; 95% CI: 2.6–6.7), advanced age (60–69 years vs 40–49 years; OR: 3.8; 95% CI: 2.0–7.0), and being underweight (body mass index <18.5 vs 18.0–24.9 kg/m(2); OR: 3.1; 95% CI: 1.0–9.4) were associated with the development of COPD. CONCLUSION: Low education status, manual labor, a history of tuberculosis and bronchiectasis, as well as male sex, advanced age and being underweight were risk factors for COPD in Korean never-smokers. Dove Medical Press 2015-03-05 /pmc/articles/PMC4356706/ /pubmed/25784796 http://dx.doi.org/10.2147/COPD.S77662 Text en © 2015 Lee et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Original Research Lee, Seok Jeong Kim, Seo Woo Kong, Kyoung Ae Ryu, Yon Ju Lee, Jin Hwa Chang, Jung Hyun Risk factors for chronic obstructive pulmonary disease among never-smokers in Korea |
title | Risk factors for chronic obstructive pulmonary disease among never-smokers in Korea |
title_full | Risk factors for chronic obstructive pulmonary disease among never-smokers in Korea |
title_fullStr | Risk factors for chronic obstructive pulmonary disease among never-smokers in Korea |
title_full_unstemmed | Risk factors for chronic obstructive pulmonary disease among never-smokers in Korea |
title_short | Risk factors for chronic obstructive pulmonary disease among never-smokers in Korea |
title_sort | risk factors for chronic obstructive pulmonary disease among never-smokers in korea |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356706/ https://www.ncbi.nlm.nih.gov/pubmed/25784796 http://dx.doi.org/10.2147/COPD.S77662 |
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