The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents

BACKGROUND AND OBJECTIVES: The gut hormones peptide YY (PYY) and glucagon-like peptide 1 (GLP-1) acutely suppress appetite. The short chain fatty acid (SCFA) receptor, free fatty acid receptor 2 (FFA2) is present on colonic enteroendocrine L cells, and a role has been suggested for SCFAs in appetite...

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Detalles Bibliográficos
Autores principales: Psichas, A, Sleeth, M L, Murphy, K G, Brooks, L, Bewick, G A, Hanyaloglu, A C, Ghatei, M A, Bloom, S R, Frost, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356745/
https://www.ncbi.nlm.nih.gov/pubmed/25109781
http://dx.doi.org/10.1038/ijo.2014.153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356745/
https://www.ncbi.nlm.nih.gov/pubmed/25109781
http://dx.doi.org/10.1038/ijo.2014.153

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