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Towards a commercial process for the manufacture of genetically modified T cells for therapy

The recent successes of adoptive T-cell immunotherapy for the treatment of hematologic malignancies have highlighted the need for manufacturing processes that are robust and scalable for product commercialization. Here we review some of the more outstanding issues surrounding commercial scale manufa...

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Detalles Bibliográficos
Autores principales: Kaiser, A D, Assenmacher, M, Schröder, B, Meyer, M, Orentas, R, Bethke, U, Dropulic, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356749/
https://www.ncbi.nlm.nih.gov/pubmed/25613483
http://dx.doi.org/10.1038/cgt.2014.78