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Tagging polyketides/non-ribosomal peptides with a clickable functionality and applications

Bioorthogonal chemistry has recently emerged to be one of the most powerful tools in drug discovery and chemical biology. The exploration of it has successfully advanced the field of natural product research. In this Perspective, we survey current strategies for the installation of chemical handles...

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Detalles Bibliográficos
Autores principales: Zhu, Xuejun, Zhang, Wenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356899/
https://www.ncbi.nlm.nih.gov/pubmed/25815285
http://dx.doi.org/10.3389/fchem.2015.00011