PERK silence inhibits glioma cell growth under low glucose stress by blockage of p-AKT and subsequent HK2's mitochondria translocation

Glioma relies on glycolysis to obtain energy and sustain its survival under low glucose microenvironment in vivo. The mechanisms on glioma cell glycolysis regulation are still unclear. Signaling mediated by Double-stranded RNA-activated protein kinase (PKR) – like ER kinase (PERK) is one of the impo...

Descripción completa

Detalles Bibliográficos
Autores principales: Hou, Xu, Liu, Yaohua, Liu, Huailei, Chen, Xin, Liu, Min, Che, Hui, Guo, Fei, Wang, Chunlei, Zhang, Daming, Wu, Jianing, Chen, Xiaofeng, Shen, Chen, Li, Chenguang, Peng, Fei, Bi, Yunke, Yang, Zhuowen, Yang, Guang, Ai, Jing, Gao, Xin, Zhao, Shiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356960/
https://www.ncbi.nlm.nih.gov/pubmed/25761777
http://dx.doi.org/10.1038/srep09065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356960/
https://www.ncbi.nlm.nih.gov/pubmed/25761777
http://dx.doi.org/10.1038/srep09065

Ejemplares similares