An adenosine A3 receptor agonist inhibits DSS-induced colitis in mice through modulation of the NF-κB signaling pathway

The role of the adenosine A3 receptor (A3AR) in experimental colitis is controversial. The A3AR agonist N(6)-(3-iodobenzyl)adenosine-5'-N-methyluronamide (IB-MECA) has been shown to have a clinical benefit, although studies in A3AR-deficient mice suggest a pro-inflammatory role. However, there...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Tianhua, Tian, Ting, Feng, Xiao, Ye, Shicai, Wang, Hao, Wu, Weiyun, Qiu, Yumei, Yu, Caiyuan, He, Yanting, Zeng, Juncheng, Cen, Junwei, Zhou, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357005/
https://www.ncbi.nlm.nih.gov/pubmed/25762375
http://dx.doi.org/10.1038/srep09047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357005/
https://www.ncbi.nlm.nih.gov/pubmed/25762375
http://dx.doi.org/10.1038/srep09047

Ejemplares similares