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Myeloperoxidase level around dental implants as an indicator of an inflammatory process

AIM: Myeloperoxidase (MPO) has been widely used as an inflammatory marker of both acute and chronic conditions. The aim of the present study was to analyze MPO found in the peri-implant sulcus fluid of implants (PISF) and gingival cervicular fluid (GCF) of natural teeth in healthy or diseased states...

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Autores principales: Durrani, Farhan, Singh, Royana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357073/
https://www.ncbi.nlm.nih.gov/pubmed/25767353
http://dx.doi.org/10.4103/0975-962X.151688
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author Durrani, Farhan
Singh, Royana
author_facet Durrani, Farhan
Singh, Royana
author_sort Durrani, Farhan
collection PubMed
description AIM: Myeloperoxidase (MPO) has been widely used as an inflammatory marker of both acute and chronic conditions. The aim of the present study was to analyze MPO found in the peri-implant sulcus fluid of implants (PISF) and gingival cervicular fluid (GCF) of natural teeth in healthy or diseased states. MATERIAL AND METHODS: A total of 107 dental implant sites, either healthy/noninflamed, inflamed or affected by periodontitis, were classified and GCF/PISF samples were obtained. GCF/PISF MPO was spectrophotometrically determined. RESULTS: Both the GCF and the PISF volumes exhibited a gradual increase with gingival inflammation (P < 0.05). PISF from inflamed sites (P = 0.0001) and GCF from the gingivitis and periodontitis sites showed significantly higher total MPO levels (P < 0.05) in comparison with the noninflamed sites. The volumetric similarities of PISF and GCF in terms of response to inflammation were seen in the present study. However, some differences in PISF and GCF were observed. CONCLUSION: PISF may be suggested to have a considerable diagnostic potential as it exhibits the biologic changes around load-bearing endosseous dental implants.
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spelling pubmed-43570732015-03-12 Myeloperoxidase level around dental implants as an indicator of an inflammatory process Durrani, Farhan Singh, Royana Indian J Dent Original Article AIM: Myeloperoxidase (MPO) has been widely used as an inflammatory marker of both acute and chronic conditions. The aim of the present study was to analyze MPO found in the peri-implant sulcus fluid of implants (PISF) and gingival cervicular fluid (GCF) of natural teeth in healthy or diseased states. MATERIAL AND METHODS: A total of 107 dental implant sites, either healthy/noninflamed, inflamed or affected by periodontitis, were classified and GCF/PISF samples were obtained. GCF/PISF MPO was spectrophotometrically determined. RESULTS: Both the GCF and the PISF volumes exhibited a gradual increase with gingival inflammation (P < 0.05). PISF from inflamed sites (P = 0.0001) and GCF from the gingivitis and periodontitis sites showed significantly higher total MPO levels (P < 0.05) in comparison with the noninflamed sites. The volumetric similarities of PISF and GCF in terms of response to inflammation were seen in the present study. However, some differences in PISF and GCF were observed. CONCLUSION: PISF may be suggested to have a considerable diagnostic potential as it exhibits the biologic changes around load-bearing endosseous dental implants. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4357073/ /pubmed/25767353 http://dx.doi.org/10.4103/0975-962X.151688 Text en Copyright: © Indian Journal of Dentistry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Durrani, Farhan
Singh, Royana
Myeloperoxidase level around dental implants as an indicator of an inflammatory process
title Myeloperoxidase level around dental implants as an indicator of an inflammatory process
title_full Myeloperoxidase level around dental implants as an indicator of an inflammatory process
title_fullStr Myeloperoxidase level around dental implants as an indicator of an inflammatory process
title_full_unstemmed Myeloperoxidase level around dental implants as an indicator of an inflammatory process
title_short Myeloperoxidase level around dental implants as an indicator of an inflammatory process
title_sort myeloperoxidase level around dental implants as an indicator of an inflammatory process
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357073/
https://www.ncbi.nlm.nih.gov/pubmed/25767353
http://dx.doi.org/10.4103/0975-962X.151688
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