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Use of nerve elongator to repair short-distance peripheral nerve defects: a prospective randomized study

Repair techniques for short-distance peripheral nerve defects, including adjacent joint flexion to reduce the distance between the nerve stump defects, “nerve splint” suturing, and nerve sleeve connection, have some disadvantages. Therefore, we designed a repair technique involving intraoperative te...

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Autores principales: Bai, Lu, Wang, Tian-bing, Wang, Xin, Zhang, Wei-wen, Xu, Ji-hai, Cai, Xiao-ming, Zhou, Dan-ya, Cai, Li-bing, Pan, Jia-dong, Tian, Min-tao, Chen, Hong, Zhang, Dian-ying, Fu, Zhong-guo, Zhang, Pei-xun, Jiang, Bao-guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357122/
https://www.ncbi.nlm.nih.gov/pubmed/25788924
http://dx.doi.org/10.4103/1673-5374.150710
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author Bai, Lu
Wang, Tian-bing
Wang, Xin
Zhang, Wei-wen
Xu, Ji-hai
Cai, Xiao-ming
Zhou, Dan-ya
Cai, Li-bing
Pan, Jia-dong
Tian, Min-tao
Chen, Hong
Zhang, Dian-ying
Fu, Zhong-guo
Zhang, Pei-xun
Jiang, Bao-guo
author_facet Bai, Lu
Wang, Tian-bing
Wang, Xin
Zhang, Wei-wen
Xu, Ji-hai
Cai, Xiao-ming
Zhou, Dan-ya
Cai, Li-bing
Pan, Jia-dong
Tian, Min-tao
Chen, Hong
Zhang, Dian-ying
Fu, Zhong-guo
Zhang, Pei-xun
Jiang, Bao-guo
author_sort Bai, Lu
collection PubMed
description Repair techniques for short-distance peripheral nerve defects, including adjacent joint flexion to reduce the distance between the nerve stump defects, “nerve splint” suturing, and nerve sleeve connection, have some disadvantages. Therefore, we designed a repair technique involving intraoperative tension-free application of a nerve elongator and obtained good outcomes in the repair of short-distance peripheral nerve defects in a previous animal study. The present study compared the clinical outcomes between the use of this nerve elongator and performance of the conventional method in the repair of short-distance transection injuries in human elbows. The 3-, 6-, and 12-month postoperative follow-up results demonstrated that early neurological function recovery was better in the nerve elongation group than in the conventional group, but no significant difference in long-term neurological function recovery was detected between the two groups. In the nerve elongation group, the nerves were sutured without tension, and the duration of postoperative immobilization of the elbow was decreased. Elbow function rehabilitation was significantly better in the nerve elongation group than in the control group. Moreover, there were no security risks. The results of this study confirm that the use of this nerve elongator for repair of short-distance peripheral nerve defects is safe and effective.
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spelling pubmed-43571222015-03-18 Use of nerve elongator to repair short-distance peripheral nerve defects: a prospective randomized study Bai, Lu Wang, Tian-bing Wang, Xin Zhang, Wei-wen Xu, Ji-hai Cai, Xiao-ming Zhou, Dan-ya Cai, Li-bing Pan, Jia-dong Tian, Min-tao Chen, Hong Zhang, Dian-ying Fu, Zhong-guo Zhang, Pei-xun Jiang, Bao-guo Neural Regen Res Special Issue Repair techniques for short-distance peripheral nerve defects, including adjacent joint flexion to reduce the distance between the nerve stump defects, “nerve splint” suturing, and nerve sleeve connection, have some disadvantages. Therefore, we designed a repair technique involving intraoperative tension-free application of a nerve elongator and obtained good outcomes in the repair of short-distance peripheral nerve defects in a previous animal study. The present study compared the clinical outcomes between the use of this nerve elongator and performance of the conventional method in the repair of short-distance transection injuries in human elbows. The 3-, 6-, and 12-month postoperative follow-up results demonstrated that early neurological function recovery was better in the nerve elongation group than in the conventional group, but no significant difference in long-term neurological function recovery was detected between the two groups. In the nerve elongation group, the nerves were sutured without tension, and the duration of postoperative immobilization of the elbow was decreased. Elbow function rehabilitation was significantly better in the nerve elongation group than in the control group. Moreover, there were no security risks. The results of this study confirm that the use of this nerve elongator for repair of short-distance peripheral nerve defects is safe and effective. Medknow Publications & Media Pvt Ltd 2015-01 /pmc/articles/PMC4357122/ /pubmed/25788924 http://dx.doi.org/10.4103/1673-5374.150710 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Special Issue
Bai, Lu
Wang, Tian-bing
Wang, Xin
Zhang, Wei-wen
Xu, Ji-hai
Cai, Xiao-ming
Zhou, Dan-ya
Cai, Li-bing
Pan, Jia-dong
Tian, Min-tao
Chen, Hong
Zhang, Dian-ying
Fu, Zhong-guo
Zhang, Pei-xun
Jiang, Bao-guo
Use of nerve elongator to repair short-distance peripheral nerve defects: a prospective randomized study
title Use of nerve elongator to repair short-distance peripheral nerve defects: a prospective randomized study
title_full Use of nerve elongator to repair short-distance peripheral nerve defects: a prospective randomized study
title_fullStr Use of nerve elongator to repair short-distance peripheral nerve defects: a prospective randomized study
title_full_unstemmed Use of nerve elongator to repair short-distance peripheral nerve defects: a prospective randomized study
title_short Use of nerve elongator to repair short-distance peripheral nerve defects: a prospective randomized study
title_sort use of nerve elongator to repair short-distance peripheral nerve defects: a prospective randomized study
topic Special Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357122/
https://www.ncbi.nlm.nih.gov/pubmed/25788924
http://dx.doi.org/10.4103/1673-5374.150710
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