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Use of nerve elongator to repair short-distance peripheral nerve defects: a prospective randomized study
Repair techniques for short-distance peripheral nerve defects, including adjacent joint flexion to reduce the distance between the nerve stump defects, “nerve splint” suturing, and nerve sleeve connection, have some disadvantages. Therefore, we designed a repair technique involving intraoperative te...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357122/ https://www.ncbi.nlm.nih.gov/pubmed/25788924 http://dx.doi.org/10.4103/1673-5374.150710 |
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author | Bai, Lu Wang, Tian-bing Wang, Xin Zhang, Wei-wen Xu, Ji-hai Cai, Xiao-ming Zhou, Dan-ya Cai, Li-bing Pan, Jia-dong Tian, Min-tao Chen, Hong Zhang, Dian-ying Fu, Zhong-guo Zhang, Pei-xun Jiang, Bao-guo |
author_facet | Bai, Lu Wang, Tian-bing Wang, Xin Zhang, Wei-wen Xu, Ji-hai Cai, Xiao-ming Zhou, Dan-ya Cai, Li-bing Pan, Jia-dong Tian, Min-tao Chen, Hong Zhang, Dian-ying Fu, Zhong-guo Zhang, Pei-xun Jiang, Bao-guo |
author_sort | Bai, Lu |
collection | PubMed |
description | Repair techniques for short-distance peripheral nerve defects, including adjacent joint flexion to reduce the distance between the nerve stump defects, “nerve splint” suturing, and nerve sleeve connection, have some disadvantages. Therefore, we designed a repair technique involving intraoperative tension-free application of a nerve elongator and obtained good outcomes in the repair of short-distance peripheral nerve defects in a previous animal study. The present study compared the clinical outcomes between the use of this nerve elongator and performance of the conventional method in the repair of short-distance transection injuries in human elbows. The 3-, 6-, and 12-month postoperative follow-up results demonstrated that early neurological function recovery was better in the nerve elongation group than in the conventional group, but no significant difference in long-term neurological function recovery was detected between the two groups. In the nerve elongation group, the nerves were sutured without tension, and the duration of postoperative immobilization of the elbow was decreased. Elbow function rehabilitation was significantly better in the nerve elongation group than in the control group. Moreover, there were no security risks. The results of this study confirm that the use of this nerve elongator for repair of short-distance peripheral nerve defects is safe and effective. |
format | Online Article Text |
id | pubmed-4357122 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-43571222015-03-18 Use of nerve elongator to repair short-distance peripheral nerve defects: a prospective randomized study Bai, Lu Wang, Tian-bing Wang, Xin Zhang, Wei-wen Xu, Ji-hai Cai, Xiao-ming Zhou, Dan-ya Cai, Li-bing Pan, Jia-dong Tian, Min-tao Chen, Hong Zhang, Dian-ying Fu, Zhong-guo Zhang, Pei-xun Jiang, Bao-guo Neural Regen Res Special Issue Repair techniques for short-distance peripheral nerve defects, including adjacent joint flexion to reduce the distance between the nerve stump defects, “nerve splint” suturing, and nerve sleeve connection, have some disadvantages. Therefore, we designed a repair technique involving intraoperative tension-free application of a nerve elongator and obtained good outcomes in the repair of short-distance peripheral nerve defects in a previous animal study. The present study compared the clinical outcomes between the use of this nerve elongator and performance of the conventional method in the repair of short-distance transection injuries in human elbows. The 3-, 6-, and 12-month postoperative follow-up results demonstrated that early neurological function recovery was better in the nerve elongation group than in the conventional group, but no significant difference in long-term neurological function recovery was detected between the two groups. In the nerve elongation group, the nerves were sutured without tension, and the duration of postoperative immobilization of the elbow was decreased. Elbow function rehabilitation was significantly better in the nerve elongation group than in the control group. Moreover, there were no security risks. The results of this study confirm that the use of this nerve elongator for repair of short-distance peripheral nerve defects is safe and effective. Medknow Publications & Media Pvt Ltd 2015-01 /pmc/articles/PMC4357122/ /pubmed/25788924 http://dx.doi.org/10.4103/1673-5374.150710 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Special Issue Bai, Lu Wang, Tian-bing Wang, Xin Zhang, Wei-wen Xu, Ji-hai Cai, Xiao-ming Zhou, Dan-ya Cai, Li-bing Pan, Jia-dong Tian, Min-tao Chen, Hong Zhang, Dian-ying Fu, Zhong-guo Zhang, Pei-xun Jiang, Bao-guo Use of nerve elongator to repair short-distance peripheral nerve defects: a prospective randomized study |
title | Use of nerve elongator to repair short-distance peripheral nerve defects: a prospective randomized study |
title_full | Use of nerve elongator to repair short-distance peripheral nerve defects: a prospective randomized study |
title_fullStr | Use of nerve elongator to repair short-distance peripheral nerve defects: a prospective randomized study |
title_full_unstemmed | Use of nerve elongator to repair short-distance peripheral nerve defects: a prospective randomized study |
title_short | Use of nerve elongator to repair short-distance peripheral nerve defects: a prospective randomized study |
title_sort | use of nerve elongator to repair short-distance peripheral nerve defects: a prospective randomized study |
topic | Special Issue |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357122/ https://www.ncbi.nlm.nih.gov/pubmed/25788924 http://dx.doi.org/10.4103/1673-5374.150710 |
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