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K-core decomposition of a protein domain co-occurrence network reveals lower cancer mutation rates for interior cores

BACKGROUND: Network biology currently focuses primarily on metabolic pathways, gene regulatory, and protein-protein interaction networks. While these approaches have yielded critical information, alternative methods to network analysis will offer new perspectives on biological information. A little...

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Detalles Bibliográficos
Autores principales: Emerson, Arnold I, Andrews, Simeon, Ahmed, Ikhlak, Azis, Thasni KA, Malek, Joel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357223/
https://www.ncbi.nlm.nih.gov/pubmed/25767694
http://dx.doi.org/10.1186/s13336-015-0016-6

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