Novel agonists for serotonin 5-HT(7) receptors reverse metabotropic glutamate receptor-mediated long-term depression in the hippocampus of wild-type and Fmr1 KO mice, a model of Fragile X Syndrome

Serotonin 5-HT(7) receptors are expressed in the hippocampus and modulate the excitability of hippocampal neurons. We have previously shown that 5-HT(7) receptors modulate glutamate-mediated hippocampal synaptic transmission and long-term synaptic plasticity. In particular, we have shown that activa...

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Detalles Bibliográficos
Autores principales: Costa, Lara, Sardone, Lara M., Lacivita, Enza, Leopoldo, Marcello, Ciranna, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357247/
https://www.ncbi.nlm.nih.gov/pubmed/25814945
http://dx.doi.org/10.3389/fnbeh.2015.00065

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