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DDR-mediated crosstalk between DNA-damaged cells and their microenvironment

The DNA damage response (DDR) is an evolutionarily conserved signaling cascade that senses and responds to double-strand DNA breaks by organizing downstream cellular events, ranging from appropriate DNA repair to cell cycle checkpoints. In higher organisms, the DDR prevents neoplastic transformation...

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Detalles Bibliográficos
Autores principales: Malaquin, Nicolas, Carrier-Leclerc, Audrey, Dessureault, Mireille, Rodier, Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357297/
https://www.ncbi.nlm.nih.gov/pubmed/25815006
http://dx.doi.org/10.3389/fgene.2015.00094