Cargando…
Manipulating the selection forces during affinity maturation to generate cross-reactive HIV antibodies
Generation of potent antibodies by a mutation-selection process called affinity maturation is a key component of effective immune responses. Antibodies that protect against highly mutable pathogens must neutralize diverse strains. Developing effective immunization strategies to drive their evolution...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357364/ https://www.ncbi.nlm.nih.gov/pubmed/25662010 http://dx.doi.org/10.1016/j.cell.2015.01.027 |